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Intrapartum epidural analgesia and ST analysis of the fetal electrocardiogram.

机译:产前硬膜外镇痛和胎儿心电图的ST分析。

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摘要

OBJECTIVE: To evaluate the influence of intrapartum epidural analgesia on the occurrence of ST events of the fetal ECG. DESIGN: Nested case-control study. SETTING: Single-centre academic hospital in the Netherlands. POPULATION: Laboring women with a high-risk singleton pregnancy in cephalic position beyond 36 weeks of gestation. METHODS: Data of 72 women who received epidural analgesia using bupivacaine combined with sufentanil and 72 control women were collected and analyzed. The moment of epidural infusion was defined as t(0) . In the control group, t(0) was defined by matching dilatation in centimeters. STAN registrations from one hour before until two hours after t(0) were classified, and the numbers and types of ST events were recorded and judged according to the STAN clinical guidelines. T/QRS ratios were collected from one hour before t(0) until two hours after t(0) , and differences were compared between the two groups. MAIN OUTCOME MEASURES: Numbers and types of ST events and mean T/QRS ratios before and after t(0). RESULTS: There were no significant differences between cases and control women regarding the numbers of ST events, types of ST events and whether they were significant (intervention advised) or not. Correction for outliers (three cases and three control women) did not change the results. Differences of T/QRS ratios before and after t(0) were comparable between cases and control women. CONCLUSIONS: Epidural analgesia has no effect on the numbers or types of ST events when using ST analysis of the fetal ECG.
机译:目的:评估产前硬膜外镇痛对胎儿心电图ST事件发生的影响。设计:嵌套病例对照研究。地点:荷兰的单中心学术医院。人口:高危单身妊娠的孕妇在妊娠36周后的头位。方法:收集并分析72例接受布比卡因联合舒芬太尼联合硬膜外镇痛的妇女和72例对照妇女的数据。硬膜外输注的时刻定义为t(0)。在对照组中,t(0)是通过以厘米为单位的匹配扩张定义的。从t(0)之前的一个小时到t(0)之后的两个小时对STAN注册进行分类,并根据STAN临床指南记录和判断ST事件的数量和类型。从t(0)之前1小时到t(0)之后2小时收集T / QRS比率,并比较两组之间的差异。主要观察指标:ST事件的数目和类型,以及t(0)之前和之后的平均T / QRS比。结果:病例和对照妇女之间在性病事件的数量,性病事件的类型以及是否显着(建议干预)方面无显着差异。校正异常值(3例和3例对照妇女)不会改变结果。在病例(t)(0)之前和之后,T / QRS比率的差异在病例组和对照妇女之间是可比的。结论:使用胎儿心电图进行ST分析时,硬膜外镇痛对ST事件的数量或类型没有影响。

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