Prospective predictors of exacerbation status in severe asthma over a 3-year follow-up

摘要

BackgroundA predisposition to exacerbations is being recognized as a distinct phenotype with previous exacerbations representing the strongest clinical factor associated with future exacerbation. Thus, to identify additional novel biomarkers associated with asthma exacerbations, past exacerbation status must be included as a confounding factor.