Ultrasonic-bath-assisted preparation of mononuclear copper(I) thiosemicarbazone complex particles: Crystal structure, characterization and antimicrobial activity

摘要

Particles of the copper(I) thiosemicarbazone complex [Cu(Brcatsc)(PPh3)2Cl]center dot CH3CN (1), Brcatsc - 2-bromo-3-phenylpropenalthiosemicarbazone, were synthesized by an ultrasonic-bath-assisted method and characterized by elemental analyses, NMR (H-1, C-13, and P-31) and FT-IR spectroscopies, X-ray powder diffraction (XRD) and scanning electron microscopy (SEM). The thermal stability of 1 was studied by thermal gravimetry analysis and its structure was determined by single crystal X-ray diffraction. The compound 1 is a mononuclear complex with the copper(I) ion coordinated in a distorted tetrahedral geometry by one S atom of Brcatsc, two P atoms of two PPh3, and one Cl atom. The complex involves the Brcatsc thiosemicarbazone ligand in an S monodentate bonding mode. The antibacterial activity of the ligand and its copper(I) complex was studied against two gram-positive (Staphylococcus aureus and Enterococcus faecalis) and two gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria. (C) 2016 Acadmie des sciences. Published by Elsevier Masson SAS. All rights reserved.