Osteonecrosis: what does it mean? One condition partly caused by bisphosphonates-or another one, preferably treated with them?

摘要

In both the scientific and the lay press (Kolata 2006), there have recently been many warnings about something called osteonecrosis of the jaw, a condition apparently related to cancer and chemotherapy in combination with bisphosphonates (Ruggiero et al. 2004, Marx et al. 2005). It is rare in relation to the widespread use of bisphosphonates, but has led to recommendations to pay attention to oral status in connection with cancer therapy when the bone contains, or will contain, bisphosphonates (Marx et al. 2005).