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How immunological profile drives clinical phenotype of primary Sjogren's syndrome at diagnosis: analysis of 10,500 patients (Sjogren Big Data Project)

机译:免疫外形如何在诊断中驱动原发性Sjogren综合征的临床表型:分析10,500名患者(Sjogren大数据项目)

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摘要

Objective. To evaluate the influence of the main immunological markers on the disease phenotype at diagnosis in a large international cohort of patients with primary Sjogren's syndrome (SjS).
机译:客观的。 评估主要免疫标志物对诊断患者诊断中的疾病表型的影响(SJS)诊断

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  • 作者单位

    Hosp CIMA Sanitas Dept Med Autoimmune Dis Unit Barcelona Spain;

    Mimar Sinan Fine Arts Univ Fac Sci &

    Letters Dept Stat Istanbul Turkey;

    Newcastle Univ Inst Cellular Med Newcastle Upon Tyne Tyne &

    Wear England;

    Univ Debrecen Fac Med Div Clin Immunol Debrecen Hungary;

    Oklahoma Med Res Fdn Arthrit &

    Clin Immunol Res Program 825 NE 13th St Oklahoma City OK 73104;

    Lund Univ Skane Univ Hosp Malmo Dept Rheumatol Malmo Sweden;

    Univ Paris Sud Hop Univ Paris Sud AP HP Ctr Immunol Viral Infect &

    Autoimmune Dis INSERM Paris;

    Anhui Prov Hosp Dept Rheumatol &

    Immunol Hefei Anhui Peoples R China;

    Univ Pisa Rheumatol Unit Pisa Italy;

    Univ Strasbourg Strasbourg Univ Hosp CNRS Dept Rheumatol Strasbourg France;

    Christian Med Coll &

    Hosp Dept Clin Immunol &

    Rheumatol Vellore Tamil Nadu India;

    Univ Hosp Santa Maria della Misericordia Dept Med Area DAME Clin Rheumatol Udine Italy;

    Sapienza Univ Rome Rheumatol Clin Dept Internal Med &

    Med Specialties Rome Italy;

    Inst Nacl Ciencias Med &

    Nutr Salvador Zubiran Dept Rheumatol &

    Immunol Mexico City DF Mexico;

    Hacettepe Univ Fac Med Dept Internal Med Ankara Turkey;

    Univ Med Ctr Utrecht Dept Rheumatol &

    Clin Immunol Utrecht Netherlands;

    Catholic Univ Korea Seoul St Marys Hosp Seoul South Korea;

    Karolinska Inst Dept Med Rheumatol Unit Stockholm Sweden;

    Univ Med Ctr Dept Rheumatol Ljubljana Slovenia;

    Paris Diderot Univ Lariboisiere Hosp AP HP Dept Internal Med Paris France;

    Univ Perugia Dept Med Rheumatol Unit Perugia Italy;

    Hosp Valle De Hebron Dept Internal Med Barcelona Spain;

    Univ Western Australia Sch Med Dept Rheumatol Crawley Australia;

    Kanazawa Univ Hosp Div Rheumatol Kanazawa Ishikawa Japan;

    UCL Div Med Ctr Rheumatol London England;

    Univ Espirito Santo Dept Med Vitoria Brazil;

    Wroclaw Med Hosp Dept Rheumatol &

    Internal Med Wroclaw Poland;

    Uppsala Univ Dept Med Sci Rheumatol Uppsala Sweden;

    Hosp Ramon &

    Cajal Dept Internal Med Madrid Spain;

    Univ Groningen Univ Med Ctr Groningen Dept Rheumatol &

    Clin Immunol Groningen Netherlands;

    Nagasaki Univ Grad Sch Biomed Sci Dept Radiol &

    Canc Biol Nagasaki Japan;

    Univ Aquila Sch Med Clin Unit Rheumatol Laquila Italy;

    Brest Univ Hosp Dept Rheumatol Brest France;

    Tech Univ Munich Klinikum Rechts Isar Otorhinolaryngol Head &

    Neck Surg Munich Germany;

    Queen Mary Univ London Ctr Expt Med &

    Rheumatol London England;

    Univ Fed Sao Paulo Sao Paulo Brazil;

    Univ Bergen Dept Clin Sci Bergen Norway;

    Univ Sao Paulo Fac Med Hosp Clin Div Rheumatol Sao Paulo Brazil;

    Univ Nacl Cordoba Consejo Nacl Invest Cient &

    Tecn CONICET Inst Invest Ciencias Salud INICSA;

    Cairo Univ Kasr Al Ainy Sch Med Dept Rheumatol Cairo Egypt;

    IRCCS Galeazzi Orthopaed Inst Milan Italy;

    Montpellier Univ Hosp Dept Rheumatol Montpellier France;

    German Hosp Buenos Aires DF Argentina;

    Univ Debrecen Fac Med Div Clin Immunol Debrecen Hungary;

    Oklahoma Med Res Fdn Arthrit &

    Clin Immunol Res Program 825 NE 13th St Oklahoma City OK 73104;

    Lund Univ Skane Univ Hosp Malmo Dept Rheumatol Malmo Sweden;

    Univ Hosp Santa Maria della Misericordia Dept Med Area DAME Clin Rheumatol Udine Italy;

    Inst Nacl Ciencias Med &

    Nutr Salvador Zubiran Dept Rheumatol &

    Immunol Mexico City DF Mexico;

    Hacettepe Univ Fac Med Dept Internal Med Ankara Turkey;

    Karolinska Inst Dept Med Rheumatol Unit Stockholm Sweden;

    Univ Paris Sud Hop Univ Paris Sud AP HP Ctr Immunol Viral Infect &

    Autoimmune Dis INSERM Paris;

    Univ Barcelona Sjogrens Syndrome Res Grp AGAUR Lab Autoimmune Dis Josep Font Hosp Clin IDIBAPS;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 免疫性疾病;
  • 关键词

    primary Sjogren's syndrome; salivary gland biopsy; Ro/La autoantibodies; hypocomplementaemia; cryoglobulinaemia; ESSDAI;

    机译:原发性Sjogren综合征;唾液腺活检;RO / LA Auto intibodies;Hypocompmentaemia;Cryoglobulinaemia;essdai;

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