Stable pH responsive layer-by-layer assemblies of partially hydrolysed poly(2-ethyl-2-oxazoline) and poly(acrylic acid) for effective prevention of protein, cell and bacteria surface attachment

Tao He; Dominik Jańczewski; Shifeng Guo; Shu Mei Man; Shan Jiang; Wui Siew Tan

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Stable pH responsive layer-by-layer assemblies of partially hydrolysed poly(2-ethyl-2-oxazoline) and poly(acrylic acid) for effective prevention of protein, cell and bacteria surface attachment

机译：部分水解的聚（2-乙基-2-恶唑啉）和聚（丙烯酸）的稳定pH响应层逐层组件，用于有效预防蛋白质，细胞和细菌表面附着

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Graphical abstract

Layer-by-layer assemblies of partially hydrolysed poly(2-ethyl-2-oxazoline) (PEOX-I) and poly(acrylic acid) (PAA) provide for effective resistance against surface protein, cell and bacterial attachment.

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Highlights

?A method to create stable coatings of poly(2-ethyl-2-oxazoline) is reported.

?Protein-, cell- and bacteria- attachment can be suppressed by these coatings.

?Coatings exhibit thickness dependent resistance to protein adsorption.

?Optimal coatings (～220nm thick) provide broad spectrum bio-fouling resistance.

Abstract

机译：<！[cdata [

图形抽象

部分水解聚（2-乙基-2-恶唑啉）（PEOX-1）和聚（丙烯酸的层）逐层组件）（PAA）提供针对表面蛋白质，细胞和细菌附着的有效抗性。显示省略

突出显示

？报告了一种制造聚（2-乙基-2-恶唑啉）稳定涂层的方法。

？蛋白质 - ，细胞和细菌可以被这些涂层抑制。

？涂料表现出厚度依赖性对蛋白质吸附的抗性。

？最佳涂层（〜220nm厚）提供广谱生物污垢抗性。

抽象 < CE：Abstract-SEC ID =“ABST0015”View =“全部”>

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来源
《Colloids and Surfaces, B. Biointerfaces》 |2018年第2018期|共10页
作者
Tao He; Dominik Jańczewski; Shifeng Guo; Shu Mei Man; Shan Jiang; Wui Siew Tan;
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作者单位

Institute of Materials Research and Engineering A*STAR (Agency for Science Technology and Research);

Laboratory of Technological Processes Faculty of Chemistry Warsaw University of Technology;

Institute of Materials Research and Engineering A*STAR (Agency for Science Technology and Research);

Institute of Materials Research and Engineering A*STAR (Agency for Science Technology and Research);

College of Chemistry Jilin University;

Institute of Materials Research and Engineering A*STAR (Agency for Science Technology and Research);

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原文格式 PDF
正文语种 eng
中图分类胶体化学（分散体系的物理化学）;
关键词
Layer-by-layer assembly; Poly(2-ethyl-2-oxazoline); Polyoxazolines; Anti-fouling; Adhesion; Protein adsorption; Responsive;

机译：逐层组装;聚（2-乙基-2-恶唑啉）;多恶唑啉;防污;粘附;蛋白质吸附;响应;

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专利

1. Stable pH responsive layer-by-layer assemblies of partially hydrolysed poly(2-ethyl-2-oxazoline) and poly(acrylic acid) for effective prevention of protein, cell and bacteria surface attachment [J] . Tao He, Dominik Jańczewski, Shifeng Guo, Colloids and Surfaces, B. Biointerfaces . 2018,第期

机译：部分水解的聚（2-乙基-2-恶唑啉）和聚（丙烯酸）的稳定pH响应层逐层组件，用于有效预防蛋白质，细胞和细菌表面附着
2. Covalent assembly of poly(ethyleneimine) via layer-by-layer deposition for enhancing surface density of protein and bacteria attachment [J] . Bing Xia, Jisen Shi, Chen Dong, Applied Surface Science . 2014,第feba15期

机译：聚乙烯（亚乙基亚胺）通过逐层沉积共价组装以增强蛋白质和细菌附着的表面密度
3. Dual stimuli-responsive Fe 3 O 4 graft poly(acrylic acid)- block -poly(2-methacryloyloxyethyl ferrocenecarboxylate) copolymer micromicelles: surface RAFT synthesis, self-assembly and drug release applications [J] . Yuan Wang, Xue-Yin Zhang, Yan-Ling Luo, Journal of Nanobiotechnology . 2017,第1期

机译：双刺激响应Fe 3 O 4接枝聚（丙烯酸）-嵌段-聚（2-甲基丙烯酰氧基乙基二茂铁羧酸酯）共聚物微胶粒：表面RAFT合成，自组装和药物释放应用
4. Novel micelle releasing systems; complex formation of poly(2-ethyl-2-oxazoline)/poly(epsilon-caprolactone) block copolymer micelles with poly(acrylic acid) [C] . S.C.Lee, I.C.Kwon, H.Chung, International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 2000

机译：新型胶束释放系统;聚（2-乙基-2-恶唑啉）/聚（ε-己内酯）嵌段共聚物胶束与聚丙烯酸的复合形成
5. Self-assembly of poly(ethylene oxide)-b-polystyrene- b-poly(acrylic acid) triblock copolymers in solution [D] . Wu, Qinghua 2006

机译：溶液中聚环氧乙烷-b-聚苯乙烯-b-聚丙烯酸三嵌段共聚物的自组装
6. Dual stimuli-responsive Fe3O4 graft poly(acrylic acid)-block-poly(2-methacryloyloxyethyl ferrocenecarboxylate) copolymer micromicelles: surface RAFT synthesis self-assembly and drug release applications [O] . Yuan Wang, Xue-Yin Zhang, Yan-Ling Luo, 2017

机译：双刺激响应的Fe3O4接枝聚丙烯酸-嵌段-聚2-甲基丙烯酰氧基乙基二茂铁羧酸酯共聚物微胶粒：表面RAFT合成自组装和药物释放应用
7. Dual stimuli-responsive Fe3O4 graft poly(acrylic acid)-block-poly(2-methacryloyloxyethyl ferrocenecarboxylate) copolymer micromicelles: surface RAFT synthesis, self-assembly and drug release applications [O] . Yuan Wang, Xue-Yin Zhang, Yan-Ling Luo, 2017

机译：双刺激响应Fe3O4接枝聚（丙烯酸） - 嵌段 - 聚（2-甲基丙烯酰氧基乙基二茂铁羧酸酯）共聚物微胶囊：表面RaFT合成，自组装和药物释放应用
8. Photophysical Investigations of Interpolymer Interactions in Solutions of a Pyrene Substituted Poly(acrylic acid), Poly(vinyl amine), Poly(l-aminoacrylic acid), and Poly(l-acetylaminoacrylic acid). [R] . Arora, K. S., Turro, N. J. 1987

机译：芘取代聚（丙烯酸），聚（乙烯胺），聚（1-氨基丙烯酸）和聚（1-乙酰氨基丙烯酸）溶液中互聚物相互作用的光物理研究。

Stable pH responsive layer-by-layer assemblies of partially hydrolysed poly(2-ethyl-2-oxazoline) and poly(acrylic acid) for effective prevention of protein, cell and bacteria surface attachment

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