The effect of thiolated phospholipids on formation of supported lipid bilayers on gold substrates investigated by surface-sensitive methods

摘要

Graphical AbstractDisplay OmittedHighlights?The binding kinetics of thiolated liposomes monitored by QCM-D and SPR methods.?Viscoelastic modelling was implemented for the optimized thiol ratio.?Spatial surface characterization studies were performed by AFM.?Thiolated lipid presence helps SLB formation without prior surface modification.?Effect of thiol presence to liposome rupture is reduced for larger liposomes.AbstractMost of the model lipid membrane studies on gold involve the usage of variou