B-15. Waveform analysis of sympathetic skin response

摘要

The author analyzed waveform of sympathetic skin response (SSR). Waveforms were classified as either the P-type, in which the positive component was larger than the negative one, or the N-type, in which the negative component was larger the positive one. P-type-SSR had shorter latency and larger amplitude than N-type-SSR. Among 50 subjects 14 and 9 ones had only the P-type and N-type during 20 electrical stimulations, respectively. The remaining 27 subjects had both types. Habituation was associated with waveform changes from P to N types. Palm-SSR had the largeer amplitude and more common appearance of P-type waveform than sole-SSR. When the stimulation was increased, the SSR size became larger. Strong responses likely produced large P-type-SSR. The waveform and size of SSR seemed to be rather consistent in individuals even if the stimulation modality was changed. SSRs from two palm sites had significantly shorter latencies and larger amplitudes than the SSRs evoked from proximal sites of the forearm (paradoxical shortening of the latency). The SSR waveform pattern was not affected by the pathological condition related to diabetes. These findings above can be explained by a model of the equivalent current dipole caused by the Na+ concentration gradient in terms of SSR generation.