P274 Pleasant and unpleasant sound perception in patients with severe and moderate TBI using correlation dimension D2 analysis

摘要

Objectives Post-traumatic emotional disorder event is a major cause of slow rehabilitation worldwide. The present study investigates the effects of pleasant and unpleasant sound stimulation at different groups of subjects with TBI. At the base of our research strategy, we had used a group with diffuse axonal injury (DAI). Neurophysiology trials aim was to determine the processes that accompany emotional changes within traumatic brain damage. Methods All the following processing was performed using EEGLab plugin for MatLab. We’ve calculated D2 of the examined signal bandpass-filtered in the whole range of interest (2–20 Hz). Filtering was conducted using forward FFT, zeroing some samples and then reverse FFT. D2 was calculated using Higuchi algorithm (Higuchi, 1998). Results Our results showed that the correlation dimension D2 was significantly lower in severe TBI compared to healthy participants at a frequency of alpha rhythm during sound stimulation, especially unpleasant sounds. Discussion Meanwhile we found group differences of common correlation dimension in the parietal occipital region as much as possible to the sound of barking and crying. This result can support the previous data showed the prevalent respond to negative stimulation in patients in coma. Conclusions The high meaning of correlation dimension D2 is associated with higher entropy of EEG. Significance Recent studies have shown that the clinical assessment of mental recovery post-traumatic patients does not reflect the narrowing of the emotional respond and greatly lower. ]]>