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Acute irradiation injury of canine brain with pathology control is detected by diffusion-weighted imaging of MRI

机译:通过MRI的扩散加权成像检测与病理学对照的急性辐照损伤

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摘要

To investigate the pathological changes of canine brain after irradiation and evaluate the effect of diffusion-weighted imaging (DWI), 25 healthy dogs were treated with 70 Gy 60Coγ-ray irradiation on right temporal brain. Respectively, the apparent diffusion coefficient (ADC) values of canine alba and ectocinerea were measured by MRI T1 weighted imaging (T1WI), T2 weighted imaging (T2WI), and DWI. Compared with the control group, at every time point after irradiation, the ADC values of canine brain tissue were decreased significantly (P05). DWI is a very sensitive imaging technology that detects the changes of water molecule diffusion and microscopic pathological changes after canine brain irradiation.
机译:为了探讨犬类脑后的病理变化,并评估扩散加权成像(DWI)的效果,在右颞大脑上用70gy60Coγ射线照射治疗25只健康犬。 分别,通过MRI T1加权成像(T1WI),T2加权成像(T2WI)和DWI测量犬秃鹰和胞外胚胎的表观扩散系数(ADC)值。 与对照组相比,在照射后的每一时间,犬脑组织的ADC值显着降低(P <05)。 DWI是一种非常敏感的成像技术,可检测犬脑照射后水分子扩散和微观病理变化的变化。

著录项

  • 来源
    《Clinical imaging》 |2013年第3期|共6页
  • 作者单位

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

    Department of Radiation Oncology JiNan Military General Hospital District TianQiao 250031 JiNan;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Acute irradiation injury; Animal experiment; Canine brain; Diffusion-weighted imaging;

    机译:急性辐照损伤;动物实验;犬脑;扩散加权成像;

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