Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer

Meade S.; Gaunt P.; Hartley A.; Robinson M.; Harrop V.; Cashmore J.; Wagstaff L.; Babrah J.; Bowden S. J.; Mehanna H.; Sanghera P.

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Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer

机译：人乳头瘤病毒 - 阴性或吸烟相关的口咽癌的剂量升高的次规化学地理的可行性

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Aims: Oropharyngeal squamous cell carcinoma (OPSCC) can be divided into favourable and poor prognostic groups by association with human papilloma virus (HPV) and smoking. This study prospectively investigated a dose-intensified schedule in poor/intermediate prognosis OPSCC.

机译：目的：口咽鳞状细胞癌（OPSCC）可以通过与人乳头瘤病毒（HPV）和吸烟分为有利和贫困的预后组。本研究预期研究了贫困/中期预后OPSCC的剂量加强的时间表。

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《Clinical oncology》 |2018年第6期|共9页
作者
Meade S.; Gaunt P.; Hartley A.; Robinson M.; Harrop V.; Cashmore J.; Wagstaff L.; Babrah J.; Bowden S. J.; Mehanna H.; Sanghera P.;
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作者单位

Univ Hosp Birmingham NHS Fdn Trust Hall Edwards Radiotherapy Res Grp Birmingham W Midlands;

Univ Birmingham CRUK Clin Trials Unit Birmingham W Midlands England;

Univ Hosp Birmingham NHS Fdn Trust Hall Edwards Radiotherapy Res Grp Birmingham W Midlands;

Newcastle Univ Sch Dent Sci Newcastle England;

Univ Hosp Birmingham NHS Fdn Trust Hall Edwards Radiotherapy Res Grp Birmingham W Midlands;

Univ Hosp Birmingham NHS Fdn Trust Hall Edwards Radiotherapy Res Grp Birmingham W Midlands;

Univ Birmingham Inst Head &

Neck Studies &

Educ InHANSE Birmingham W Midlands England;

Univ Birmingham CRUK Clin Trials Unit Birmingham W Midlands England;

Univ Birmingham CRUK Clin Trials Unit Birmingham W Midlands England;

Univ Birmingham Inst Head &

Neck Studies &

Educ InHANSE Birmingham W Midlands England;

Univ Hosp Birmingham NHS Fdn Trust Hall Edwards Radiotherapy Res Grp Birmingham W Midlands;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Accelerated hypofractionation; human papilloma virus; oropharyngeal cancer; smoking;

机译：加速次规;人乳头状瘤病毒;口咽癌症;吸烟;

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专利

1. Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer [J] . Meade S., Gaunt P., Hartley A., Clinical oncology . 2018,第6期

机译：人乳头瘤病毒 - 阴性或吸烟相关的口咽癌的剂量升高的次规化学地理的可行性
2. Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer [J] . Meade S., Gaunt P., Hartley A., Clinical oncology . 2018,第6期

机译：人乳头瘤病毒 - 阴性或吸烟相关的口咽癌的剂量升高的次规化学地理的可行性
3. Bcl2 and Human Papilloma Virus 16 as Predictors of Outcome following Concurrent Chemoradiation for Advanced Oropharyngeal Cancer [J] . Anthony C. Nichols, Dianne M. Finkelstein, William C. Faquin, Clinical cancer research: an official journal of the American Association for Cancer Research . 2010,第7期

机译：Bcl2和人类乳头瘤病毒16作为晚期口咽癌同时放化疗后结果的预测因子。
4. Protein differences associated with human papilloma virus status in oropharyngeal squamous cell carcinoma (OSCC) [C] . Nico Jehmlich, Brandee Brown, Wendell G. Yarbrough, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：与口咽鳞状细胞癌（OSCC）中的人乳头瘤病毒状态相关的蛋白质差异
5. Human papilloma virus infection and cervical cancer: Elucidation of a causal relation through the use of molecular biology and epidemiological research. [D] . Moraros, John S. 2007

机译：人类乳头瘤病毒感染和宫颈癌：通过分子生物学和流行病学研究阐明因果关系。
6. Characterization of high risk human papilloma virus genotypes associated with oropharyngeal cancers in a Nigerian population [O] . Benjamin Idemudia Akhiwu, Helen Oluwadamilola Akhiwu, Tolulope Afolaranmi, 2021

机译：尼日利亚人口中患有口咽癌症的高风险人乳头瘤菌基因型的特征
7. Feasibility of PET-CT based hypofractionated accelerated dose escalation in oropharyngeal cancers: Final dosimetric results of the VORTIGERN study. (Secondary endpoint of UK NCRI portfolio: MREC No: 08/H0907/127, UKCRN ID 7341) [O] . Sanjoy Chatterjee, Charles Kelly, Moses Arunsingh, 2015

机译：在口咽癌中基于pET-CT的大分割加速剂量递增的可行性：VORTIGERN研究的最终剂量测定结果。（英国NCRI投资组合的次要终点：mREC No：08 / H0907 / 127，UKCRN ID 7341）

Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer

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