SINGLE- AND MULTIPLE-DOSE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN IN HEALTHY ADULT AND ELDERLY SUBJECTS.

Sidharta P.; Kankam M.; Dingemanse J.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >SINGLE- AND MULTIPLE-DOSE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN IN HEALTHY ADULT AND ELDERLY SUBJECTS.

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SINGLE- AND MULTIPLE-DOSE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN IN HEALTHY ADULT AND ELDERLY SUBJECTS.

机译：在健康成人和老年人的双内皮受体拮抗剂Aprocitentan的单剂和多剂量安全，药代动力学和药效学。

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来源
《Clinical Pharmacology and Therapeutics》 |2018年第1期|共1页
作者
Sidharta P.; Kankam M.; Dingemanse J.;
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作者单位

Idorsia Pharmaceut Inc Cherry Hill NJ USA;

Vince &

Associates Clin Res Inc Overland Pk KS USA;

Idorsia Pharmaceut Ltd Allschwil Switzerland;

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原文格式 PDF
正文语种 eng
中图分类药理学;
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1. SINGLE- AND MULTIPLE-DOSE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN IN HEALTHY ADULT AND ELDERLY SUBJECTS. [J] . Sidharta P., Kankam M., Dingemanse J. Clinical Pharmacology and Therapeutics . 2018,第Suppla1期

机译：在健康成人和老年人的双内皮受体拮抗剂Aprocitentan的单剂和多剂量安全，药代动力学和药效学。
2. SINGLE- AND MULTIPLE-DOSE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN IN HEALTHY ADULT AND ELDERLY SUBJECTS. [J] . Sidharta P., Kankam M., Dingemanse J. Clinical Pharmacology and Therapeutics . 2018,第Suppla1期

机译：在健康成人和老年人的双内皮受体拮抗剂Aprocitentan的单剂和多剂量安全，药代动力学和药效学。
3. Single- and multiple-dose tolerability, safety, pharmacokinetics, and pharmacodynamics of the dual endothelin receptor antagonist aprocitentan in healthy adult and elderly subjects [J] . Patricia N Sidharta, Meggane Melchior, Martin K Kankam, Drug Design, Development and Therapy . 2019,第InaProgress期

机译：双重内皮素受体拮抗剂aprocitentan在健康成人和老年受试者中的单剂量和多剂量耐受性，安全性，药代动力学和药效学
4. Safety, tolerability, pharmacodynamics and pharmacokinetics following single subcutaneous dosesof a teverelix depot formulation in healthy male volunteers [C] . C. MacLean, F. Larsen, R. Piechatzek, Annual meeting exposition of the Controlled Release Society . 2005

机译：在健康男性志愿者中单次皮下注射Teverelix储库制剂后的安全性，耐受性，药效动力学和药代动力学
5. Addition of leukotriene receptor antagonists versus long acting beta agonists to inhaled corticosteroid therapy for asthma treatment in older adults: A retrospective data analysis of effectiveness, safety and cost. [D] . Altawalbeh, Shoroq Mahmoud. 2015

机译：在吸入性糖皮质激素治疗中，将白三烯受体拮抗剂与长效β激动剂相比，用于老年人的哮喘治疗：有效性，安全性和成本的回顾性数据分析。
6. Single- and multiple-dose tolerability safety pharmacokinetics and pharmacodynamics of the dual endothelin receptor antagonist aprocitentan in healthy adult and elderly subjects [O] . Patricia N Sidharta, Meggane Melchior, Martin K Kankam, 2019

机译：双重内皮素受体拮抗剂aprocitentan在健康成人和老年受试者中的单剂量和多剂量耐受性安全性药代动力学和药效学
7. 0007 Multiple-Ascending-Dose Study Of ACT-541468, A Novel Dual Orexin Receptor Antagonist: Characterization Of Its Multiple-Dose Pharmacokinetics, Pharmacodynamics, Safety, And Tolerability [O] . C Muehlan, S Brooks, R Zuiker, 2018

机译：0007 ACT-541468的多次上升剂量研究，一种新型双羊酸蛋白受体拮抗剂：其多剂量药代动力学，药效学，安全性和耐受性的表征

SINGLE- AND MULTIPLE-DOSE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN IN HEALTHY ADULT AND ELDERLY SUBJECTS.

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