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Molecular Tumor Boards: Realizing Precision Oncology Therapy

机译:分子肿瘤板:实现精密肿瘤学疗法

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摘要

Technological advances in high-throughput next-generation sequencing (NGS) along with advances in computational processes have brought about the dawn of the genomic medicine era. NGS has enabled molecular characterization of malignancies, and facilitated the development and approval of gene- and immune-targeted therapies, both of which impact the mutanome. Clinical implementation of this technology, approval of novel targeted agents, and establishment of molecular tumor boards has enabled precision oncology to become a reality.
机译:高通量下一代测序(NGS)的技术进步以及计算过程的进步引起了基因组医学时代的曙光。 NGS使恶性肿瘤的分子表征能够促进基因和免疫靶向疗法的发展和批准,这两者都影响了异种组。 这种技术的临床实施,新型靶向剂的批准以及分子肿瘤板的建立使得能够成为现实。

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    Univ Calif San Diego Skaggs Sch Pharm &

    Pharmaceut Sci La Jolla CA 92093 USA;

    Univ Calif San Diego Ctr Personalized Canc Therapy Moores Canc Ctr La Jolla CA 92093 USA;

    Univ Calif San Diego Ctr Personalized Canc Therapy Moores Canc Ctr La Jolla CA 92093 USA;

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  • 正文语种 eng
  • 中图分类 药理学;
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