DISPOSITION OF [14C]ETRASIMOD FOLLOWING ORAL ADMINISTRATION TO HEALTHY MALE VOLUNTEERS AND ROLE OF CYP2C IN FORMATION OF OXIDATIVE METABOLITES.

Lee C.; Oh D.; Tang Y.; Blackburn A.; Bloom S.; Cabell C.; Gilder K.; Grundy J.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >DISPOSITION OF [14C]ETRASIMOD FOLLOWING ORAL ADMINISTRATION TO HEALTHY MALE VOLUNTEERS AND ROLE OF CYP2C IN FORMATION OF OXIDATIVE METABOLITES.

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DISPOSITION OF [14C]ETRASIMOD FOLLOWING ORAL ADMINISTRATION TO HEALTHY MALE VOLUNTEERS AND ROLE OF CYP2C IN FORMATION OF OXIDATIVE METABOLITES.

机译：在口服给予口服给予健康雄性志愿者和CYP2C在形成氧化代谢物后的作用。

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《Clinical Pharmacology and Therapeutics》 |2020年第s1期|共1页
作者
Lee C.; Oh D.; Tang Y.; Blackburn A.; Bloom S.; Cabell C.; Gilder K.; Grundy J.;
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作者单位

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

Arena Pharmaceut San Diego CA USA;

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正文语种 eng
中图分类药理学;
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1. DISPOSITION OF [14C]ETRASIMOD FOLLOWING ORAL ADMINISTRATION TO HEALTHY MALE VOLUNTEERS AND ROLE OF CYP2C IN FORMATION OF OXIDATIVE METABOLITES. [J] . Lee C., Oh D., Tang Y., Clinical Pharmacology and Therapeutics . 2020,第S1期

机译：在口服给予口服给予健康雄性志愿者和CYP2C在形成氧化代谢物后的作用。
2. Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers. [J] . Strandgarden K, strazeneca.com, Hoglund P, Biopharmaceutics and Drug Disposition . 2000,第2期

机译：对健康志愿者口服后（14C）roquinimex的吸收和处置，包括肝肠循环。
3. Absorption, metabolism and excretion of [ 14C]mirabegron (YM178), a potent and selective β 3-adrenoceptor agonist, after oral administration to healthy male volunteers [J] . Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2012,第4期

机译：对健康男性志愿者口服后，一种有效的选择性β3肾上腺素受体激动剂[14 C]米拉贝隆（YM178）的吸收，代谢和排泄
4. A Phase I, Double-Blind, Randomized, Dose Escalating Crossover Study ofan Oral Formulation of Human Growth Hormone in Healthy Male Volunteers [C] . Steven M. Dinh, Puchun Liu, Ehud Arbit, Controlled Release Society annual meeting . 2004

机译：健康男性志愿者中人类生长激素口服制剂的I期，双盲，随机，剂量递增交叉研究
5. Evaluation of the role of oxidative stress, inflammation and apoptosis in the pulmonary and the hepatic toxicity induced by cerium oxide nanoparticles following intratracheal instillation in male Sprague-Dawley rats [D] . Nalabotu, Siva Krishna 2012

机译：评价氧化应激，炎症和细胞凋亡在雄性Sprague-Dawley大鼠气管内滴注后氧化铈纳米颗粒诱发的肺部毒性和肝毒性中的作用
6. Pulmonary Disposition of Tedizolid following Administration of Once-Daily Oral 200-Milligram Tedizolid Phosphate in Healthy Adult Volunteers [O] . Seth T. Housman, J. Samuel Pope, John Russomanno, 2012

机译：在健康成人志愿者中每天口服一次200毫克的磷酸替地唑啉磷酸盐后对替硝唑胺进行肺部处置
7. Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J Mice [O] . Pickup, K, Martin, S, Partridge, EA, 2016

机译：口服给予正常和胆汁插管的雄性C57BL / 6J小鼠后[14C] - 芬兰酸的急性肝脏作用，处置和代谢命运

DISPOSITION OF [14C]ETRASIMOD FOLLOWING ORAL ADMINISTRATION TO HEALTHY MALE VOLUNTEERS AND ROLE OF CYP2C IN FORMATION OF OXIDATIVE METABOLITES.

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