VOLUME OF DISTRIBUTION IS UNAFFECTED BY DRUG-DRUG INTERACTION STUDIES FOR METABOLIZED DRUGS ALLOWING DIFFERENTIATION OF CLEARANCE AND BIOAVAILABILITY CHANGES FOR ORAL DRUGS.

Sodhi J.; Benet L.; Huang C.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >VOLUME OF DISTRIBUTION IS UNAFFECTED BY DRUG-DRUG INTERACTION STUDIES FOR METABOLIZED DRUGS ALLOWING DIFFERENTIATION OF CLEARANCE AND BIOAVAILABILITY CHANGES FOR ORAL DRUGS.

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VOLUME OF DISTRIBUTION IS UNAFFECTED BY DRUG-DRUG INTERACTION STUDIES FOR METABOLIZED DRUGS ALLOWING DIFFERENTIATION OF CLEARANCE AND BIOAVAILABILITY CHANGES FOR ORAL DRUGS.

机译：分配量不受代谢药物的药物 - 药物相互作用研究的影响，允许分化间隙和口腔药物的生物利用度变化。

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来源
《Clinical Pharmacology and Therapeutics》 |2020年第s1期|共1页
作者
Sodhi J.; Benet L.; Huang C.;
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作者单位

Univ Calif San Francisco San Francisco CA 94143 USA;

Univ Calif San Francisco San Francisco CA 94143 USA;

Univ Calif San Francisco San Francisco CA 94143 USA;

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正文语种 eng
中图分类药理学;
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1. VOLUME OF DISTRIBUTION IS UNAFFECTED BY DRUG-DRUG INTERACTION STUDIES FOR METABOLIZED DRUGS ALLOWING DIFFERENTIATION OF CLEARANCE AND BIOAVAILABILITY CHANGES FOR ORAL DRUGS. [J] . Sodhi J., Benet L., Huang C. Clinical Pharmacology and Therapeutics . 2020,第S1期

机译：分配量不受代谢药物的药物 - 药物相互作用研究的影响，允许分化间隙和口腔药物的生物利用度变化。
2. pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions. [J] . Kis O, Zastre JA, Ramaswamy M, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2010,第3期

机译：Caco-2细胞中有机阴离子运输多肽2B1的pH依赖性：在抗逆转录病毒药物口服生物利用度和药物相互作用中的潜在作用。
3. Cassette dosing for pharmacokinetic screening in drug discovery: comparison of clearance, volume of distribution, half-life, mean residence time, and oral bioavailability obtained by cassette and discrete dosing in rats. [J] . Nagilla R, Nord M, McAtee JJ, Journal of pharmaceutical sciences. . 2011,第9期

机译：在药物发现中进行药代动力学筛选的盒式给药：通过盒式和离散式给药在大鼠中获得的清除率，分布量，半衰期，平均停留时间和口服生物利用度的比较。
4. Design of PEG PEG-grafted grafted-PLA nanoparticles as bioavailability enhancer for orally administrated drugs. [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：PEG PEG接枝移植PLA纳米粒子的设计为口服给药的生物利用度增强剂。
5. Novel in vitro cell culture models for studying pharmacokinetic drug-drug interactions following oral administration [D] . Kwatra, Deep 2011

机译：用于研究口服给药后药代动力学药物相互作用的新型体外细胞培养模型
6. When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interactions [O] . Gabriela I. Patilea-Vrana, Jashvant D. Unadkat -1

机译：药物肝清除率的决定性步骤何时从正弦吸收转变为所有肝胆清除率？预测药物相互作用的意义
7. A Simple Methodology to Differentiate Changes in Bioavailability From Changes in Clearance Following Oral Dosing of Metabolized Drugs [O] . Jasleen K. Sodhi, Leslie Z. Benet 2020

机译：一种简单的方法，以在口服给药后的间隙变化中区分生物利用度的变化

VOLUME OF DISTRIBUTION IS UNAFFECTED BY DRUG-DRUG INTERACTION STUDIES FOR METABOLIZED DRUGS ALLOWING DIFFERENTIATION OF CLEARANCE AND BIOAVAILABILITY CHANGES FOR ORAL DRUGS.

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