F-18-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer Correlation With Multiparametric MRI and Histopathology

Turkbey Baris; Mena Esther; Lindenberg Liza; Adler Stephen; Bednarova Sandra; Berman Rose; Ton Anita T.; McKinney Yolanda; Eclarinal Philip; Hill Craig; Afari George; Bhattacharyya Sibaprasad; Mease Ronnie C.; Merino Maria J.; Jacobs Paula M.; Wood Bradford J.; Pinto Peter A.; Pomper Martin G.; Choyke Peter L.

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F-18-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer Correlation With Multiparametric MRI and Histopathology

机译：F-18-DCFBC前列腺特异性膜抗原靶向PET / CT成像在局部前列腺癌相关性与多射周MRI和组织病理学相关

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摘要

Purpose: To assess the ability of (N-[N-[(S)-1,3-dicarboxypropyl] carbamoyl]4-F-18-fluorobenzyl-L-cysteine) (F-18-DCFBC), a prostate-specific membrane antigen-targeted PET agent, to detect localized prostate cancer lesions in correlation with multiparametric MRI (mpMRI) and histopathology.

机译：目的：评估（n- [n - [n - [n - [（s）-1,3-二羧基丙基-1-半胱氨酸4-f-18-氟苄基-1-半胱氨酸）的能力）（f-18-dcfbc），一种特异性的膜抗原靶向PET剂，以检测与多丙基MRI（MPMRI）和组织病理学相关的局部前列腺癌病变。

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来源
《Clinical nuclear medicine》 |2017年第10期|共6页
作者
Turkbey Baris; Mena Esther; Lindenberg Liza; Adler Stephen; Bednarova Sandra; Berman Rose; Ton Anita T.; McKinney Yolanda; Eclarinal Philip; Hill Craig; Afari George; Bhattacharyya Sibaprasad; Mease Ronnie C.; Merino Maria J.; Jacobs Paula M.; Wood Bradford J.; Pinto Peter A.; Pomper Martin G.; Choyke Peter L.;
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作者单位

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

Leidos Biomed Res Inc Clin Res Directorate Clin Monitoring Res Program Frederick MD USA;

Univ Udine Inst Diagnost Radiol Dept Med Area Udine Italy;

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

NCI Ctr Canc Res Off Clin Director Bethesda MD 20892 USA;

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

Leidos Biomed Res Inc Frederick Natl Lab Canc Res Appl Dev Res Directorate Frederick MD USA;

Leidos Biomed Res Inc Frederick Natl Lab Canc Res Appl Dev Res Directorate Frederick MD USA;

FDA CDER Off Pharmaceut Qual Silver Spring MD USA;

Johns Hopkins Med Inst Russell H Morgan Dept Radiol &

Radiol Sci 600 N Wolfe St Baltimore MD;

NCI Pathol Lab Bldg 10 Bethesda MD 20892 USA;

NCI Div Canc Treatment &

Diag Rockville MD USA;

Natl Canc Inst &

Clin Ctr Ctr Intervent Oncol Bethesda MD USA;

NCI Urol Oncol Branch Bethesda MD 20892 USA;

Johns Hopkins Med Inst Russell H Morgan Dept Radiol &

Radiol Sci 600 N Wolfe St Baltimore MD;

NCI Mol Imaging Program Bldg 10 Room B3B69F Bethesda MD 20892 USA;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
F-18-DCFBC PET/CT; multiparametric prostate MRI; prostate cancer; PSMA;

机译：F-18-DCFBC PET / CT;多前列腺前列腺MRI;前列腺癌;PSMA;

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专利

1. F-18-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer Correlation With Multiparametric MRI and Histopathology [J] . Turkbey Baris, Mena Esther, Lindenberg Liza, Clinical nuclear medicine . 2017,第10期

机译：F-18-DCFBC前列腺特异性膜抗原靶向PET / CT成像在局部前列腺癌相关性与多射周MRI和组织病理学相关
2. Ga-68 Prostate-specific Membrane Antigen PET/CT for Primary Diagnosis of Prostate Cancer: Complementary or Alternative to Multiparametric MR Imaging Response [J] . Turkbey Baris, Choyke Peter L. Radiology . 2018,第2期

机译：GA-68前列腺特异性膜抗原PET / CT用于前列腺癌的初步诊断：互补或替代的多次MR成像反应
3. Ga-68 Prostate-specific Membrane Antigen PET/CT for Primary Diagnosis of Prostate Cancer: Complementary or Alternative to Multiparametric MR Imaging [J] . Lopci Egesta, Guazzoni Giorgio, Lazzeri Massimo Radiology . 2018,第2期

机译：GA-68前列腺特异性膜抗原PET / CT用于前列腺癌的初步诊断：互补或替代的多分类MR成像
4. Long-circulating prostate-specific membrane antigen-targeted NIR phototheranostic agent [C] . Marta Overchuk, Kara M. Harmatys, Martha P. F. Damen, International Photodynamic Association World Congress;Society of Photo-Optical Instrumentation Engineers;International Photodynamic Association . 2019

机译：长循环前列腺特异性膜抗原靶向的近红外光热敏剂
5. Role of Multiparametric MRI and MRI-US Fusion to Diagnosis Clinically Significant Prostate Cancer [D] . Lu, Amanda Jane. 2019

机译：Multiparametric MRI和MRI-US融合对诊断临床显着的前列腺癌的作用
6. Comparison of 68Ga-HBED-CC PSMA-PET/CT and multiparametric MRI for gross tumour volume detection in patients with primary prostate cancer based on slice by slice comparison with histopathology [O] . Constantinos Zamboglou, Vanessa Drendel, Cordula A. Jilg, 2017

机译：基于切片与组织病理学比较的68Ga-HBED-CC PSMA-PET / CT和多参数MRI在原发性前列腺癌患者总肿瘤体积检测中的比较
7. 68Ga Prostate-specific Membrane Antigen PET/CT for Primary Diagnosis of Prostate Cancer: Complementary or Alternative to Multiparametric MR Imaging [O] . Egesta Lopci, Giorgio Guazzoni, Massimo Lazzeri 2018

机译：68GA前列腺特异性膜抗原PET / CT用于前列腺癌的初步诊断：互补或替代多射出的MR成像

F-18-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer Correlation With Multiparametric MRI and Histopathology

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