FDOPA Patterns in Adrenal Glands A Pictorial Essay

摘要

F-18-FDOPA is a well-established tool to explore pheochromocytomas. It tends to replace I-123-MIBG scan in metastatic pheochromocytomas, multiple endocrine neoplasia type 2-related tumors, succinate dehydrogenase [ubiquinone] iron-sulfur subunit-negative tumors, and succinate dehydrogenase-positive lesions. To our knowledge, no study has characterized physiological and pathological adrenal glands with F-18-FDOPA from a quantitative point of view. We report the features of different normal and pathological adrenal glands with F-18-FDOPA. Within our series, only pheochromocytomas present a significantly increased uptake reflecting the high specificity of this tracer. Tumors such as adenomas or myelolipomas present no F-18-FDOPA significant accumulation. Interestingly, adrenal gland hyperplasia and solitary glands do not demonstrate compensatory uptake.