Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A

Shah Anita; Solms Alexander; Garmann Dirk; Katterle Yvonne; Avramova Verzhiniya; Simeonov Stanislav; Lissitchkov Toshko

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Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A

机译：改进的药代动力学与海湾81-8973与脂肪激烃因子（重组）血浆/白蛋白的方法：严重血友病患者的随机药代动力学研究

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Background BAY 81-8973 is a full-length, unmodified, recombinant human factor VIII (FVIII) for the treatment of hemophilia A.

机译：背景Bay 81-8973是一种全长，未经修复的重组人因子VIII（FVIII），用于治疗血友病A.

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《Clinical pharmacokinetics》 |2017年第9期|共11页
作者
Shah Anita; Solms Alexander; Garmann Dirk; Katterle Yvonne; Avramova Verzhiniya; Simeonov Stanislav; Lissitchkov Toshko;
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Bayer 100 Bayer Blvd Whippany NJ 07981 USA;

Bayer AG Berlin Germany;

Bayer AG Wuppertal Germany;

Bayer AG Berlin Germany;

Specialized Hosp Act Treatment Hematol Dis Sofia Bulgaria;

Specialized Hosp Act Treatment Hematol Dis Sofia Bulgaria;

Specialized Hosp Act Treatment Hematol Dis Sofia Bulgaria;

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正文语种 eng
中图分类药理学;
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1. Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A [J] . Shah Anita, Solms Alexander, Garmann Dirk, Clinical pharmacokinetics . 2017,第9期

机译：改进的药代动力学与海湾81-8973与脂肪激烃因子（重组）血浆/白蛋白的方法：严重血友病患者的随机药代动力学研究
2. Erratum: Prophylaxis and quality of life in patients with hemophilia A during routine treatment with ADVATE [antihemophilic factor (recombinant), plasma/albumin-free method] in Germany: A subgroup analysis of the ADVATE PASS post-approval, non-interventional study (Annals of Hematology (2013) 92 (689-698) DOI: 10.1007/s00277-013-1678-4) [J] . PollmannH., KlamrothR., VidovicN., Annals of hematology . 2013,第7期

机译：勘误：德国ADVATE [抗血友病因子（重组），无血浆/白蛋白的方法]常规治疗期间A型血友病患者的预防和生活质量：ADVATE PASS批准后非干预研究的亚组分析（血液学年鉴（2013）92（689-698）DOI：10.1007 / s00277-013-1678-4）
3. Antihemophilic factor (recombinant) plasma/albumin-free method for the management and prevention of bleeding episodes in patients with hemophilia A [J] . Steven Pipe Biologics: Targets and Therapy . 2009,第1期

机译：抗血友病因子（重组）无血浆/白蛋白方法治疗和预防A型血友病患者出血事件
4. Factor VllhC Measurement - Comparison between chromogenic and coagulometric Methods in Hemophilia A-Patients with the B-Domain depleted recombinant F VIII-Preparation ReFacto [C] . A. Siegemund, T. Siegemund, U. Scholz, Hemophilie-Symposion . 2003

机译：因子VLLHC测量 - 血友病患者血友病患者的色情和凝血法的比较鉴定重组F VIII制剂refacto
5. Satisfaction, Adherence, and Recombinant Factor VIII Choice of Patients with Moderate to Severe Hemophilia A [D] . Strickland, Kimberly. 2020

机译：满意度，依从性和重组因素VIII患者中度至重度血友病的患者
6. Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A [O] . Anita Shah, Alexander Solms, Dirk Garmann, -1

机译：BAY 81-8973与抗血友病因子（重组）血浆/不含白蛋白的方法相比可改善药代动力学：A型严重血友病患者的随机药代动力学研究
7. Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A [O] . 2016

机译：BAY 81-8973与抗血友病因子（重组）血浆/不含白蛋白的方法相比，可改善药代动力学：A型严重血友病患者的随机药代动力学研究

Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A

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