Comparative Effectiveness of Vancomycin Versus Daptomycin for MRSA Bacteremia With Vancomycin MIC > 1 mg/L: A Multicenter Evaluation

Moise Pamela A.; Culshaw Darren L.; Wong-Beringer Annie; Bensman Joyce; Lamp Kenneth C.; Smith Winter J.; Bauer Karri; Goff Debra A.; Adamson Robert; Leuthner Kimberly; Virata Michael D.; McKinnell James A.; Chaudhry Saira B.; Eskandarian Romic; Lodise Thomas; Reyes Katherine; Zervos Marcus J.

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Comparative Effectiveness of Vancomycin Versus Daptomycin for MRSA Bacteremia With Vancomycin MIC > 1 mg/L: A Multicenter Evaluation

机译：万古霉素对达达菌霉素的对比效果与万能菌丝MIC> 1 mg / L：多中心评价

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Purpose: Clinical studies comparing vancomycin with alternative therapy for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia are limited. The objective of this study was to compare outcomes of early daptomycin versus vancomycin treatment for MRSA bacteremia with high vancomycin MICs in a geographically diverse multicenter evaluation.

机译：目的：临床研究比较万古霉素与甲氧西林金黄色葡萄球菌（MRSA）菌血症的替代治疗有限。本研究的目的是将早期达达霉素与万长霉素治疗的结果进行比较，在地理位置多中心评估中具有高万霉素MICS的MRSA菌丝治疗。

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来源
《Clinical therapeutics》 |2016年第1期|共15页
作者
Moise Pamela A.; Culshaw Darren L.; Wong-Beringer Annie; Bensman Joyce; Lamp Kenneth C.; Smith Winter J.; Bauer Karri; Goff Debra A.; Adamson Robert; Leuthner Kimberly; Virata Michael D.; McKinnell James A.; Chaudhry Saira B.; Eskandarian Romic; Lodise Thomas; Reyes Katherine; Zervos Marcus J.;
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作者单位

Merck &

Co Inc Dept Med Affairs Kenilworth NJ USA;

Merck &

Co Inc Dept Med Affairs Kenilworth NJ USA;

Univ So Calif Dept Clin Pharm &

Pharmaceut Econ &

Policy Los Angeles CA USA;

Univ So Calif Dept Clin Pharm &

Pharmaceut Econ &

Policy Los Angeles CA USA;

Merck &

Co Inc Dept Med Affairs Kenilworth NJ USA;

Univ Oklahoma Coll Pharm Dept Pharm Clin &

Adm Sci Oklahoma City OK USA;

Ohio State Univ Wexner Med Ctr Dept Pharm Columbus OH 43210 USA;

Ohio State Univ Wexner Med Ctr Dept Pharm Columbus OH 43210 USA;

St Barnabas Hlth Care Syst Dept Pharm Livingston NJ USA;

Univ Med Ctr Southern Nevada Dept Clin Pharm Las Vegas NV USA;

Yale New Haven Hosp SRC Div Infect Dis New Haven CT USA;

LA Biomed Res Inst Div Infect Dis &

Infect Dis Clin Outcomes Res Torrance Mem Med Ctr Torrance;

Jersey Shore Univ Med Ctr Dept Pharm Practice &

Adm Neptune NJ USA;

Glendale Adventist Med Ctr Dept Pharm Glendale CA USA;

Albany Coll Pharm Albany NY USA;

Henry Ford Hosp Div Infect Dis Detroit MI 48202 USA;

Henry Ford Hosp Div Infect Dis Detroit MI 48202 USA;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
daptomycin; high MIC; multicenter; MRSA bacteremia; vancomycin;

机译：达达霉素;高麦克风;多中心;MRSA菌血症;万古霉素;

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专利

1. Comparative Effectiveness of Vancomycin Versus Daptomycin for MRSA Bacteremia With Vancomycin MIC > 1 mg/L: A Multicenter Evaluation [J] . Moise Pamela A., Culshaw Darren L., Wong-Beringer Annie, Clinical therapeutics . 2016,第1期

机译：万古霉素MIC> 1 mg / L时万古霉素与达托霉素对MRSA细菌血症的比较有效性：多中心评估
2. Bactericidal activity of daptomycin versus vancomycin in the presence of human albumin against vancomycin-susceptible but tolerant methicillin-resistant Staphylococcus aureus (MRSA) with daptomycin minimum inhibitory concentrations of 1-2 mu g/mL [J] . Torrico M., Gimenez M. J., Gonzalez N., International journal of antimicrobial agents . 2010,第2期

机译：达托霉素与万古霉素在人白蛋白存在下对耐万古霉素但耐甲氧西林的金黄色葡萄球菌（MRSA）的杀菌活性，达托霉素的最低抑菌浓度为1-2μg / mL
3. A Retrospective Comparison of Daptomycin Thrice-Weekly versus Q48H Dosing in Hemodialysis Patients with Vancomycin-Resistant Enterococcus (VRE) or Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia [J] . Katie L Axford, Dane L Shiltz Advances in Pharmacology and Pharmacy . 2014,第1期

机译：耐万古霉素肠球菌（VRE）或耐甲氧西林金黄色葡萄球菌（MRSA）细菌性血液透析患者每周达托霉素三次和Q48H剂量的回顾性比较
4. A Reduction of Extended-Spectrum Beta-Lactamase Carrying Bacteria (ESBL),Methicillin-Resistant Staphylococcus aureus(MRSA)and Vancomycin-Resistant Enterococci(VRE)by Biogas Plants? [C] . KaempferP, SchaussT, WingsT, 16th International congress on animal hygiene : animal hygiene, health and welfare as corner stones of sustainable animal production . 2013

机译：沼气厂减少了广谱β-内酰胺酶携带细菌（ESBL），耐甲氧西林金黄色葡萄球菌（MRSA）和耐万古霉素肠球菌（VRE）的作用？
5. Pharmaceutical guideline compliance and its impact on costs and effectiveness: Case studies of orders based on vancomycin use and intravenous to oral switch antimicrobial guidelines at The Ohio State University Medical Center. [D] . Grauer, Dennis Wade. 2000

机译：药物指南的依从性及其对成本和有效性的影响：俄亥俄州立大学医学中心基于万古霉素使用和静脉转口服抗生素指南的案例研究。
6. 673Comparative Effectiveness of Vancomycin vs Early Daptomycin for MRSA Bacteremia with Vancomycin MIC 1 mg/L: A Multicenter Evaluation [O] . Pamela Moise, Darren Culshaw, Annie Wong-Beringer, 2014

机译：673万古霉素MIC 1 mg / L的万古霉素与早期达托霉素对MRSA细菌血症的比较效果：多中心评估
7. PIN30 ECONOMIC EVALUATION OF DAPTOMYCIN AS FIRST-LINE THERAPY VERSUS DAPTOMYCIN AS RESCUE THERAPY AFTER VANCOMYCIN OR LINEZOLID FAILURE IN GRAM-POSITIVE BACTEREMIA TREATMENT [O] . Lahoz R, Galera J, Font B, 2010

机译：PIN30对一线治疗的达莫霉素的经济评价与在革兰氏阳性细菌治疗中万古霉素或利奈唑胺失败后多巴霉素作为一线治疗的经济评价
8. Guideline for the Prevention and Management of Methicillin-Resistant Staphylococcus aureus (MRSA), Vancomycin-Resistant Enterococcus (VRE), and Vancomycin-Intermediate/Resistant Staphyloccocus aureus (VISA/VRSA) in Indiana Health Care [R] . 2004

机译：印第安纳州医疗保健中预防和管理耐甲氧西林金黄色葡萄球菌（mRsa），耐万古霉素肠球菌（VRE）和万古霉素中间/抗性金黄色葡萄球菌（VIsa / VRsa）的指南

Comparative Effectiveness of Vancomycin Versus Daptomycin for MRSA Bacteremia With Vancomycin MIC > 1 mg/L: A Multicenter Evaluation

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