A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma

Yang Zijian; LaRiviere Michael J.; Ko Jina; Till Jacob E.; Christensen Theresa; Yee Stephanie S.; Black Taylor A.; Tien Kyle; Lin Andrew; Shen Hanfei; Bhagwat Neha; Herman Daniel; Adallah Andrew; OHara Mark H.; Vollmer Charles M.; Katona Bryson W.; Stanger Ben Z.; Issadore David; Carpenter Erica L.

首页> 外文期刊>Clinical cancer research: an official journal of the American Association for Cancer Research >A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma

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A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma

机译：由细胞外囊泡miRNA和MRNA，CFDNA和CA19-9组成的多显纳利面板显示胰腺导管腺癌的诊断和分期

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Purpose: To determine whether a multianalyte liquid biopsy can improve the detection and staging of pancreatic ductal adenocarcinoma (PDAC).

机译：目的：确定多层液体活检是否可以改善胰腺导管腺癌（PDAC）的检测和分段。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2020年第13期|共11页
作者
Yang Zijian; LaRiviere Michael J.; Ko Jina; Till Jacob E.; Christensen Theresa; Yee Stephanie S.; Black Taylor A.; Tien Kyle; Lin Andrew; Shen Hanfei; Bhagwat Neha; Herman Daniel; Adallah Andrew; OHara Mark H.; Vollmer Charles M.; Katona Bryson W.; Stanger Ben Z.; Issadore David; Carpenter Erica L.;
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作者单位

Univ Penn Sch Engn &

Appl Sci Dept Mech Engn &

Appl Mech Philadelphia PA 19104 USA;

Univ Penn Dept Radiat Oncol Perelman Sch Med Philadelphia PA 19104 USA;

Univ Penn Sch Engn &

Appl Sci Dept Bioengn Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

Univ Penn Sch Engn &

Appl Sci Dept Bioengn Philadelphia PA 19104 USA;

Univ Penn Sch Engn &

Appl Sci Dept Bioengn Philadelphia PA 19104 USA;

Univ Penn Dept Med Div Gastroenterol Perelman Sch Med Philadelphia PA 19104 USA;

Univ Penn Dept Pathol &

Lab Med Perelman Sch Med Philadelphia PA USA;

Univ Penn Sch Engn &

Appl Sci Dept Bioengn Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

Hosp Univ Penn Dept Surg Div Gen Surg 3400 Spruce St Philadelphia PA 19104 USA;

Univ Penn Dept Med Div Gastroenterol Perelman Sch Med Philadelphia PA 19104 USA;

Univ Penn Dept Med Div Gastroenterol Perelman Sch Med Philadelphia PA 19104 USA;

Univ Penn Sch Engn &

Appl Sci Dept Bioengn Philadelphia PA 19104 USA;

Univ Penn Dept Med Perelman Sch Med Div Hematol Oncol Philadelphia PA 19104 USA;

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正文语种 eng
中图分类肿瘤学;
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1. A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma [J] . Yang Zijian, LaRiviere Michael J., Ko Jina, Clinical cancer research: an official journal of the American Association for Cancer Research . 2020,第13期

机译：由细胞外囊泡miRNA和MRNA，CFDNA和CA19-9组成的多显纳利面板显示胰腺导管腺癌的诊断和分期
2. Utility of serum CA19-9 levels in the diagnosis of pancreatic ductal adenocarcinoma in an endoscopic ultrasound referral population [J] . ParikhD.A., Durbin-JohnsonB., UrayamaS. Journal of gastrointestinal cancer. . 2014,第1期

机译：血清CA19-9水平在内镜超声转诊人群中诊断胰管腺癌的实用性
3. Utility of HNF-1B and a panel of lineage-specific biomarkers to optimize the diagnosis of pancreatic ductal adenocarcinoma [J] . Shi Bai, James Lindberg, Giles Whalen, American Journal of Cancer Research . 2021,第3期

机译：HNF-1B的效用和谱系特异性生物标志物的小组，优化胰腺导管腺癌的诊断
4. Biomarker development for pancreatic ductal adenocarcinoma using integrated analysis of mRNA and miRNA expression [C] . Min-Seok Kwon, Yongkang Kim, Seungyeoun Lee, IEEE International Conference on Bioinformatics and Biomedicine . 2014

机译：利用mRNA和miRNA表达的综合分析开发胰腺导管腺癌的生物标志物
5. The CA19-9 Antigen and sTRA Glycans Define Independent Pancreatic Ductal Adenocarcinoma Subpopulations Improving Diagnostic Accuracy and Approach to Prognostic Classification [D] . Barnett, Daniel Mark. 2020

机译：Ca19-9抗原和stra聚糖定义独立的胰腺导管腺癌群，提高了预后分类的诊断准确性和方法
6. Utility of Serum CA19-9 Levels in the Diagnosis of Pancreatic Ductal Adenocarcinoma in an Endoscopic Ultrasound Referral Population [O] . Dhavan A. Parikh, Blythe Durbin-Johnson, Shiro Urayama -1

机译：血清CA19-9水平在超声内镜转诊人群胰腺导管腺癌诊断中的应用
7. A panel of miRNAs derived from plasma extracellular vesicles as novel diagnostic biomarkers of lung adenocarcinoma [O] . Bing Yao, Shuang Qu, Ruifeng Hu, 2019

机译：衍生自血浆细胞外囊泡的miRNA小组作为肺腺癌的新型诊断生物标志物
8. Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma. Comparative Effectiveness Review Number 141 [R] . 2014

机译：胰腺癌的诊断和分期影像学检查。比较效力审查编号141

A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma

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