Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib

Kraft Ira L.; Akshintala Srivandana; Zhu Yuelin; Lei Haiyan; Derse-Anthony Claudia; Dombi Eva; Steinberg Seth M.; Lodish Maya; Waguespack Steven G.; Kapustina Oxana; Fox Elizabeth; Balis Frank M.; Merino Maria J.; Meltzer Paul S.; Glod John W.; Shern Jack F.; Widemann Brigitte C.

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Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib

机译：儿童和青少年的成果，具有Vandetanib治疗的先进遗传性髓质甲状腺癌

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Purpose: Vandetanib is well-tolerated in patients with advanced medullary thyroid carcinoma (MTC). Long-term outcomes and mechanisms of MTC progression have not been reported previously.

机译：目的：vandetanib在晚期髓质甲状腺癌（MTC）的患者中是良好的耐受性。之前尚未报道长期结果和MTC进展的机制。

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来源
《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2018年第4期|共13页
作者
Kraft Ira L.; Akshintala Srivandana; Zhu Yuelin; Lei Haiyan; Derse-Anthony Claudia; Dombi Eva; Steinberg Seth M.; Lodish Maya; Waguespack Steven G.; Kapustina Oxana; Fox Elizabeth; Balis Frank M.; Merino Maria J.; Meltzer Paul S.; Glod John W.; Shern Jack F.; Widemann Brigitte C.;
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作者单位

NCI Pediat Oncol Branch Ctr Canc Res Bethesda MD 20892 USA;

NYU Dept Pediat Langone Med Ctr New York NY 10016 USA;

NCI Genet Branch Ctr Canc Res Bethesda MD 20892 USA;

NCI Pediat Oncol Branch Ctr Canc Res Bethesda MD 20892 USA;

Leidos Biomed Res Inc Clin Monitoring Res Program Clin Res Directorate NCI Campus Frederick;

NCI Pediat Oncol Branch Ctr Canc Res Bethesda MD 20892 USA;

NCI Biostat &

Data Management Sect Ctr Canc Res Bethesda MD 20892 USA;

Eunice Kennedy Shriver Natl Inst Child Hlth &

Hum Dev Endocrine Oncol &

Genet Bethesda MD USA;

Univ Texas MD Anderson Canc Ctr Dept Endocrine Neoplasia &

Hormonal Disorders Houston TX 77030;

Harris IT Serv Clin Res Sterling VA USA;

Childrens Hosp Philadelphia Div Oncol Philadelphia PA 19104 USA;

Childrens Hosp Philadelphia Div Oncol Philadelphia PA 19104 USA;

NCI Translat Surg Pathol Sect Ctr Canc Res Bethesda MD 20892 USA;

NCI Genet Branch Ctr Canc Res Bethesda MD 20892 USA;

NCI Pediat Oncol Branch Ctr Canc Res Bethesda MD 20892 USA;

NCI Pediat Oncol Branch Ctr Canc Res Bethesda MD 20892 USA;

NCI Pediat Oncol Branch Ctr Canc Res Bethesda MD 20892 USA;

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正文语种 eng
中图分类肿瘤学;
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专利

1. Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib [J] . Kraft Ira L., Akshintala Srivandana, Zhu Yuelin, Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第4期

机译：儿童和青少年的成果，具有Vandetanib治疗的先进遗传性髓质甲状腺癌
2. Predictive Value of F-18-FDG PET in Patients with Advanced Medullary Thyroid Carcinoma Treated with Vandetanib [J] . Werner Rudolf A., Schmid Jan-Stefan, Higuchi Takahiro, The Journal of Nuclear Medicine . 2018,第5期

机译：用vandetanib治疗术治疗晚期髓质甲状腺癌患者F-18-FDG PET的预测值
3. Body Composition Variation and Impact of Low Skeletal Muscle Mass in Patients With Advanced Medullary Thyroid Carcinoma Treated With Vandetanib: Results From a Placebo-Controlled Study [J] . Marie-Hélène Massicotte, Isabelle Borget, Sophie Broutin, The journal of clinical endocrinology and metabolism . 2013,第6期

机译：Vandetanib治疗的晚期甲状腺髓样癌患者的身体成分变化和低骨骼肌质量的影响：安慰剂对照研究的结果
4. Coexistence of Medullary Carcinoma and Papillary Carcinoma in the Same Lobe of the Thyroid: A Rare Case Report [C] . Qiang Zhang, Yaoqi Wang, Xianying Meng, International Conference on Information Technology in Medicine and Education . 2016

机译：甲状腺同一叶中的髓样癌和乳头状癌共存：罕见病例报告
5. Distinct roles for members of the trk neurotrophin receptor family in the biology of medullary thyroid carcinoma. [D] . McGregor, Lisa MacNabb. 1998

机译：trk神经营养蛋白受体家族成员在甲状腺髓样癌生物学中的不同作用。
6. Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib [O] . Ira L Kraft, Srivandana Akshintala, Yuelin Zhu, -1

机译：Vandetanib治疗晚期遗传性甲状腺髓样癌的儿童和青少年的结果
7. Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib [O] . Ira L. Kraft, Srivandana Akshintala, Yuelin Zhu, 2017

机译：儿童和青少年的成果，具有Vandetanib治疗的先进遗传性髓质甲状腺癌

Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib

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