FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression

Hsu Chia-Ying; Chang Gee-Chen; Chen Yi-Ju; Hsu Yi-Chiung; Hsiao Yi-Jing; Su Kang-Yi; Chen Hsuan-Yu; Lin Chien-Yu; Chen Jin-Shing; Chen Yu-Ju; Hong Qi-Sheng; Ku Wen-Hui; Wu Chih-Ying; Ho Bing-Ching; Chiang Ching-Cheng; Yang Pan-Chyr; Yu Sung-Liang

首页> 外文期刊>Clinical cancer research: an official journal of the American Association for Cancer Research >FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression

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FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression

机译：FAM198B通过堵塞ERK介导的MMP-1表达延长生存和抑制肺腺癌中的转移相关

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Purpose: The comprehensive understanding of mechanisms involved in the tumor metastasis is urgently needed for discovering novel metastasis-related genes for developing effective diagnoses and treatments for lung cancer.

机译：目的：迫切需要了解肿瘤转移的机制的综合理解，用于发现新型转移相关基因，用于制定用于肺癌的有效诊断和治疗方法。

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来源
《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2018年第4期|共11页
作者
Hsu Chia-Ying; Chang Gee-Chen; Chen Yi-Ju; Hsu Yi-Chiung; Hsiao Yi-Jing; Su Kang-Yi; Chen Hsuan-Yu; Lin Chien-Yu; Chen Jin-Shing; Chen Yu-Ju; Hong Qi-Sheng; Ku Wen-Hui; Wu Chih-Ying; Ho Bing-Ching; Chiang Ching-Cheng; Yang Pan-Chyr; Yu Sung-Liang;
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作者单位

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

Natl Yang Ming Univ Sch Med Fac Med Taipei Taiwan;

Acad Sinica Inst Chem Taipei Taiwan;

Natl Cent Univ Dept Biomed Sci &

Engn Taoyuan Taiwan;

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

Natl Taiwan Univ Coll Med Ctr Genom Med Taipei Taiwan;

Natl Taiwan Univ Coll Med Ctr Genom Med Taipei Taiwan;

Natl Taiwan Univ Hosp Div Thorac Surg Taipei Taiwan;

Acad Sinica Inst Chem Taipei Taiwan;

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

Natl Taiwan Univ Coll Med 1 Chang Te St Taipei 10048 Taiwan;

Taichung Vet Gen Hosp Dept Pathol &

Lab Med Taichung Taiwan;

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

Natl Taiwan Univ Coll Med Ctr Genom Med Taipei Taiwan;

Natl Taiwan Univ Coll Med Dept Clin &

Lab Sci &

Med Biotechnol Taipei Taiwan;

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正文语种 eng
中图分类肿瘤学;
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专利

1. FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression [J] . Hsu Chia-Ying, Chang Gee-Chen, Chen Yi-Ju, Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第4期

机译：FAM198B通过堵塞ERK介导的MMP-1表达延长生存和抑制肺腺癌中的转移相关
2. Survival of lung cancer patients is prolonged with higher regucalcin gene expression: suppressed proliferation of lung adenocarcinoma A549 cells in vitro [J] . Yamaguchi Masayoshi, Osuka Satoru, Shoji Mamoru, Molecular and Cellular Biochemistry: An International Journal for Chemical Biology . 2017,第1a2期

机译：肺癌患者的存活率延长了较高的荧光素基因表达：体外抑制肺腺癌A549细胞的增殖
3. Metastasis suppressor 1 (MTSS1) expression is associated with reduced in-vivo metastasis and enhanced patient survival in lung adenocarcinoma [J] . Taylor Matthew D., Bollt Oana, Iyer Soumya C., Clinical and experimental metastasis . 2018,第1a2期

机译：转移抑制剂1（MTSS1）表达与减少的体内转移和增强肺腺癌的患者存活有关
4. Concurrent analysis of copy number variations and expression profiles to identify genes associated with tumorigenesis and survival outcome in lung adenocarcinoma [C] . 2010 IEEE International Conference on Bioinformatics and Biomedicine . 2010

机译：同时分析拷贝数变异和表达谱，以鉴定与肺腺癌的肿瘤发生和生存结果相关的基因
5. Gene expression analysis of human non -small cell lung cancer subtypes, adenocarcinoma and squamous cell carcinoma, and mouse lung epithelial cell lines: Implications in lung tumorigenesis [D] . Silvers, Amy Lynn. 2002

机译：人类非小细胞肺癌亚型，腺癌和鳞状细胞癌以及小鼠肺上皮细胞系的基因表达分析：在肺肿瘤发生中的意义
6. Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis [O] . Suet Y. Leung, Xin Chen, Kent M. Chu, 2002

机译：磷脂酶A2 IIA组在胃腺癌中的表达与延长生存期和减少转移相关
7. Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis [O] . Leung, Suet Y., Chen, Xin, Chu, Kent M., 2002

机译：磷脂酶A2 IIA组在胃腺癌中的表达与延长生存期和减少转移相关

FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression

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