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首页> 外文期刊>Clinical cancer research: an official journal of the American Association for Cancer Research >Safety, Efficacy, and Biomarker Analysis of Toripalimab in Previously Treated Advanced Melanoma: Results of the POLARIS-01 Multicenter Phase II Trial
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Safety, Efficacy, and Biomarker Analysis of Toripalimab in Previously Treated Advanced Melanoma: Results of the POLARIS-01 Multicenter Phase II Trial

机译：在先前治疗的先进黑色素瘤中的安全性，疗效和生物标志物分析oripimab：Polaris-01多中心第二期试验的结果

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摘要

Purpose: In contrast to the predominant chronic UV exposure-induced cutaneous melanoma in Caucasians, acral and mucosal comprise the majority of melanomas in Asia and respond less effectively to established treatments. The clinical application of PD-1 blockade is yet to be explored in metastatic melanoma in China.
机译：目的：与高加索人中的主要慢性紫外线暴露诱导的皮肤黑素瘤相反，亚尖锐和粘膜在亚洲的大多数黑色素瘤中包含了大多数黑色素瘤，并对建立的治疗造成的减少作出反应。 PD-1阻断的临床应用尚未在中国转移的黑素瘤探索。

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  • 作者

    Tang Bixia; Chi Zhihong; Chen Yingbo; Liu Xiufeng; Wu Di; Chen Jing; Song Xin; Wang Weifeng; Dong Lihou; Song Haifeng; Wu Hai; Feng Hui; Yao Sheng; Qin Shuikui; Zhang Xiaoshi; Guo Jun;

  • 作者单位

    Peking Univ Canc Hosp &

    Inst Key Lab Carcinogenesis &

    Translat Res Dept Renal Canc &

    Melanoma;

    Peking Univ Canc Hosp &

    Inst Key Lab Carcinogenesis &

    Translat Res Dept Renal Canc &

    Melanoma;

    Sun Yat sen Univ Guangzhou Peoples R China;

    Nanjing Bayi Hosp Nanjing Peoples R China;

    First Hosp Jilin Univ Changchun Peoples R China;

    Huazhong Univ Sci &

    Technol Union Hosp Tongji Med Coll Canc Ctr Wuhan Peoples R China;

    Tumor Hosp Yunnan Prov Kunming Yunnan Peoples R China;

    OrigiMed Shanghai Peoples R China;

    Beijing Inst Radiat Med Dept Pharmacol &

    Toxicol Beijing Peoples R China;

    Beijing Inst Radiat Med Dept Pharmacol &

    Toxicol Beijing Peoples R China;

    Shanghai Junshi Biosci Co LTD Shanghai Peoples R China;

    Shanghai Junshi Biosci Co LTD Shanghai Peoples R China;

    Shanghai Junshi Biosci Co LTD Shanghai Peoples R China;

    Nanjing Bayi Hosp Nanjing Peoples R China;

    Sun Yat sen Univ Guangzhou Peoples R China;

    Peking Univ Canc Hosp &

    Inst Key Lab Carcinogenesis &

    Translat Res Dept Renal Canc &

    Melanoma;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 肿瘤学;
  • 关键词

  • 入库时间 2022-08-19 23:44:53

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