Hyperpolarized [1-C-13]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

Scroggins Bradley T.; Matsuo Masayuki; White Ayla O.; Saito Keita; Munasinghe Jeeva P.; Sourbier Carole; Yamamoto Kazutoshi; Diaz Vivian; Takakusagi Yoichi; Ichikawa Kazuhiro; Mitchell James B.; Krishna Murali C.; Citrin Deborah E.

首页> 外文期刊>Clinical cancer research: an official journal of the American Association for Cancer Research >Hyperpolarized [1-C-13]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

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Hyperpolarized [1-C-13]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

机译：体内前列腺癌的超极化[1-C-13] - 吡合物磁共振分光谱显像预测靶向Warburg效果的功效

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Purpose: To evaluate the potential of hyperpolarized [1-C-13]-pyruvate magnetic resonance spectroscopic imaging (MRSI) of prostate cancer as a predictive biomarker for targeting the Warburg effect.

机译：目的：评估前列腺癌的超极化[1-C-13] - 吡氏碱基磁共振光谱成像（MRSI）作为针对Warburg效应的预测生物标志物。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2018年第13期|共12页
作者
Scroggins Bradley T.; Matsuo Masayuki; White Ayla O.; Saito Keita; Munasinghe Jeeva P.; Sourbier Carole; Yamamoto Kazutoshi; Diaz Vivian; Takakusagi Yoichi; Ichikawa Kazuhiro; Mitchell James B.; Krishna Murali C.; Citrin Deborah E.;
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作者单位

NCI Radiat Oncol Branch Ctr Canc Res NIH Bldg 10 Bethesda MD 20892 USA;

NCI Radiat Biol Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

NCI Radiat Oncol Branch Ctr Canc Res NIH Bldg 10 Bethesda MD 20892 USA;

NCI Radiat Biol Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

NINDS NIH Bldg 36 Rm 4D04 Bethesda MD 20892 USA;

NIH Urol Oncol Branch Ctr Canc Res Bldg 10 Bethesda MD 20892 USA;

NCI Radiat Biol Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

NINDS NIH Bldg 36 Rm 4D04 Bethesda MD 20892 USA;

Natl Inst Quantum &

Radiol Sci &

Technol Natl Inst Radiol Sci Dept Mol Imaging &

Theranost Chiba;

Nagasaki Int Univ Fac Pharmaceut Sci Dept Pharm Nagasaki Japan;

NCI Radiat Biol Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

NCI Radiat Biol Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

NCI Radiat Oncol Branch Ctr Canc Res NIH Bldg 10 Bethesda MD 20892 USA;

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正文语种 eng
中图分类肿瘤学;
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专利

1. Hyperpolarized [1-C-13]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect [J] . Scroggins Bradley T., Matsuo Masayuki, White Ayla O., Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第13期

机译：体内前列腺癌的超极化[1-C-13] - 吡合物磁共振分光谱显像预测靶向Warburg效果的功效
2. C-13 Magnetic Resonance Spectroscopic Imaging of Hyperpolarized [1-C-13, U-H-2(5)] Ethanol Oxidation can be Used to Assess Aldehyde Dehydrogenase Activity In Vivo [J] . Dzien Piotr, Kettunen Mikko I., Marco-Rius Irene, Magnetic resonance in medicine: official journal of the Society of Magnetic Resonance in Medicine . 2015,第5期

机译：超极化[1-C-13，U-H-2（5）]乙醇氧化的C-13磁共振波谱成像可用于评估体内醛脱氢酶的活性
3. Hyperpolarized 1-[ 13 C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Androgen Ablation Therapy in Prostate Cancer [J] . Rahul Aggarwal, Daniel B. Vigneron, John Kurhanewicz European urology . 2017,第6期

机译：超极化的1- [13 c] - 吡合物磁共振成像检测前列腺癌中雄激素消融治疗的早期代谢反应
4. A Met a-Classifier for Detecting Prostate Cancer by Quantitative Integration of In Vivo Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging [C] . Satish Viswanath, Pallavi Tiwari, Mark Rosen, Conference on Medical Imaging 2008: Computer-Aided Diagnosis; 20080219-21; San Diego,CA(US) . 2008

机译：一种通过体内磁共振波谱和磁共振成像定量积分检测前列腺癌的Met分类器
5. 13C Magnetic Resonance Imaging and Hyperpolarization Techniques for High-Resolution In Vivo pH Mapping in Preclinical Models of Prostate Cancer. [D] . Korenchan, David Edward. 2017

机译：前列腺癌临床前模型中高分辨率体内pH映射的13C磁共振成像和超极化技术。
6. In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous 18F-FDG-PET and Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect [O] . Henrik Gutte, Adam E. Hansen, Majbrit M.E. Larsen, 2015

机译：同时具有18F-FDG-PET和超极化13C-丙酮酸核磁共振波谱成像（hyperPET）的犬癌患者体内肿瘤代谢的表型分析：错配表明FDG不一定能反映出Warburg效应
7. Hyperpolarized 1-13C-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect [O] . Bradley T. Scroggins, Masayuki Matsuo, Ayla O. White, 2018

机译：超极化1-13c - 吡嗪型磁共振磁共振分光谱成像在体内前列腺癌预测靶向Warburg效果的疗效

Hyperpolarized [1-C-13]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

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