ICP-MS measurement of toxic and essential elements in human breast milk. A comparison of alkali dilution and acid digestion sample preparation methods

摘要

Background: For trace element measurement in human breast milk, an accurate high-throughput sample preparation method would be desirable. In this study, a quick alkali sample dilution method was systematically compared to the traditional acid digestion pretreatment for measuring 10 trace elements in 237 human breast milk samples by inductively coupled plasma mass spectrometry (ICP-MS).