Microbial toxins: Cyanobacterial toxins - From biosynthesis to function [Cyanobakterielle Toxine - von der Biosynthese zur Funktion: Mikrobielle Toxine]

摘要

Cyanobacteria are infamous for the production of potent toxins, among them the widespread hepatotoxins microcystin and nodularin. The recent assignment of biosynthetic pathways to these cyclic peptides has allowed detailed investigations into evolution, regulation, and function of these toxins. Knowledge on the biosynthetic genes provides a basis for the advancement of detection techniques for toxic cyanobacteria. Inter - disciplinary approaches support the idea of an important intracellular role of the toxin in oxidative stress acclimation and low inorganic carbon adaptation.