Antioxidants against sepsis

摘要

During sepsis, cells are swamped with reactive oxygen species generated in an aberrant response of the immune system to a local infection. If this fatal inflammatory path could be interfered with, new treatment schemes could be developed. Now, Korean scientists report in Angewandte Chemie (https://doi.org/10.1002/anie.201704904) that zirconia-doped ceria nanoparticles act as effective scavengers of these oxygen radicals, promoting a greatly enhanced surviving rate in sepsis model organisms.