PREPARATION AND NITRATION OF ALLOBETULIN seco-DERIVATIVES

摘要

2-Nitro-derivatives of allobetulone were prepared by reaction of allobetulin with nitric acid. 2β-Aminoallobetulin was synthesized by reduction of 2-nitrobetulone with LiAlH_4. The corresponding allobetulin seco-derivatives were obtained via oxidation by H_2O_2 in the presence of K_2CO_3 of 2-nitroallobetulone and cleavage of 2,2-dinitroallobetulone by K_2CO_3 in H_2O:THF.