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On the evolution of scale-free topologies with a gene regulatory network model

机译:利用基因调控网络模型研究无尺度拓扑

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摘要

A novel approach to generating scale-free network topologies is introduced, based on an existing artificial gene regulatory network model. From this model, different interaction networks can be extracted, based on an activation threshold. By using an evolutionary computation approach, the model is allowed to evolve, in order to reach specific network statistical measures. The results obtained show that, when the model uses a duplication and divergence initialisation, such as seen in nature, the resulting regulation networks not only are closer in topology to scale-free networks, but also require only a few evolutionary cycles to achieve a satisfactory error Value.
机译:基于现有的人工基因调控网络模型,介绍了一种生成无尺度网络拓扑的新颖方法。从该模型,可以基于激活阈值提取不同的交互网络。通过使用进化计算方法,模型可以进化,以达到特定的网络统计指标。所获得的结果表明,当模型使用重复和发散初始化时(如在自然界中看到的那样),所得的调节网络不仅在拓扑上更接近于无标度网络,而且仅需要几个演化周期即可获得令人满意的结果。错误值。

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