Disinfectant efficacy testing for bacterial endospores against hydrogen peroxide

摘要

Effective cleaning and disinfection of pharmaceutical and healthcare facilities requires effective practices and appropriate biocides. Application is typically through the use of two biocides in rotation. The expectation is that one disinfectant is sporicidal, not least because the presence of spore-forming bacteria poses a contamination risk due to the ability of these organisms to survive harsh environmental conditions. An example sporicide is hydrogen peroxide. It is incumbent upon each user to assess the selected sporicide for efficacy; however, developing a suitable test is not straightforward. This paper provides an approach that can be adopted for developing a sporicidal efficacy test against bacterial endospores, using hydrogen peroxide as the test sporicidal disinfectant.