Depleting stabilized GOF mutant p53 proteins by inhibiting molecular folding chaperones: a new promise in cancer therapy

Alexandrova Evguenia M.; Moll Ute M.

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Depleting stabilized GOF mutant p53 proteins by inhibiting molecular folding chaperones: a new promise in cancer therapy

机译：通过抑制分子折叠伴侣耗尽稳定的GOF突变P53蛋白：癌症治疗中的新许可

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《Cell death and differentiation》 |2017年第1期|共3页
作者
Alexandrova Evguenia M.; Moll Ute M.;
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SUNY Stony Brook Dept Pathol 101 Nicolls Rd Stony Brook NY 11794 USA;

SUNY Stony Brook Dept Pathol 101 Nicolls Rd Stony Brook NY 11794 USA;

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原文格式 PDF
正文语种 eng
中图分类细胞生物学;
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1. Depleting stabilized GOF mutant p53 proteins by inhibiting molecular folding chaperones: a new promise in cancer therapy [J] . Alexandrova Evguenia M., Moll Ute M. Cell death and differentiation . 2017,第1期

机译：通过抑制分子折叠伴侣耗尽稳定的GOF突变P53蛋白：癌症治疗中的新许可
2. Statin as anti-cancer therapy in autochthonous T-lymphomas expressing stabilized gain-of-function mutant p53 proteins [J] . Karis Tutuska, Laura Parrilla-Monge, Erica Di Cesare, Cell death & disease. . 2020,第4期

机译：他汀类蛋白作为抗癌疗法，表达稳定的函数突变体p53蛋白的稳定性曲米
3. Identification of a druggable protein–protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1 [J] . Xin Tong, Dandan Xu, Rama K. Mishra, The Journal of biological chemistry . 2021,第48期

机译：鉴定突变体P53和其稳定伴侣DNAJA1之间的可药物蛋白质 - 蛋白相互作用位点
4. Blocking the protein folding machinery. Rational design of inhibitors of the molecular chaperone Hsp90 as new anticancer agents [C] . G. COLOMBO International School of Physics "Enrico Fermi" . 2007

机译：阻止蛋白质折叠机械。作为新抗癌剂的分子伴侣HSP90抑制剂的理性设计
5. RS-41, A multi-targeted kinase inhibitor, induces cell cycle arrest and apoptosis in P53 mutant and wild type models of upper gastrointestinal cancers. [D] . Visal, Tanvi. 2017

机译：RS-41是一种多靶点激酶抑制剂，在上消化道癌的P53突变型和野生型模型中诱导细胞周期停滞和凋亡。
6. Depleting stabilized GOF mutant p53 proteins by inhibiting molecular folding chaperones: a new promise in cancer therapy [O] . Evguenia M Alexandrova, Ute M Moll 2017

机译：通过抑制分子折叠伴侣耗尽稳定的GOF突变体p53蛋白：癌症治疗的新希望
7. The Physical Association of Multiple Molecular Chaperone Proteins with Mutant p53 Is Altered by Geldanamycin, an hsp90-Binding Agent [O] . Whitesell, Luke, Sutphin, Patrick D., Pulcini, Elizabeth J., 1998

机译：hsp90结合剂格尔德霉素改变了多种分子伴侣蛋白与突变p53的物理联系。

Depleting stabilized GOF mutant p53 proteins by inhibiting molecular folding chaperones: a new promise in cancer therapy

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