Cytopathological diagnosis of hyalinizing trabecular tumour, a rare thyroid neoplasm

摘要

Dear Editor, The term 'hyalinizing trabecular adenoma' (HTA) was used by Carney et al. to describe a rare thyroid tumour, which, although usually benign, may morphologically mimic malignant thyroid neoplasms, especially papillary and medujrlary carcinoma. The present case was correctly diagnosed as 'hyalinizing trabecular tumour' (HTT) on cytology smears. The diagnosis was subsequently confirmed on histology and by ultrastructural assessment.A 25-year-old man presented with a midline neck swelling of 5 months' duration, measuring 3 x 2 cm. There was no cervical lymphadenopathy. On radio-iodine scan, it was a cold nodule within the thyroid gland. Fine needle aspiration smears frorn this nodule were haemorrhagic and moderately, cellular, with tumour cells arranged as small loosely cohesive aggregates and focally as follicle-like structures around a central core of acellular material, which appeared magenta and pale green on May-Grtinwald-Giemsa (MGG) and Papanicolaou stains, respectively (Figure la,b). This material also formed lumpy deposits between tumour cell aggregates.