Modified sequential Helicobacter Pylori eradication therapy using high dose omeprazole and amoxicillin in the initial phase in the extensive metaboliser turkish patients for CYP2C19 polymorphism is ineffective

摘要

Aim : To investigate whether the sequential therapy composed of high dose omeprazole and high dose amoxicillin in the first step was effective in eradication of H. pylori and whether there was a relation between effectiveness of the therapy and CYP2C19 gene polymorphism.