INTRODUCTION: Direct endometrial sampling with cytology and or histology is used at our hospital as part of the investigation of abnormal uterine bleeding. It is used in cases where there is a low clinical suspicion of malignancy. The advantage of the technique is that it can be done as an outpatient procedure with minimal patient discomfort. Reports in the literature give mixed results. We present a 3-year retrospective of our experience with follow-up. Table 1. Result Cytology Biopsy Follow-up histology Inadequate 9 9 One ovarian adenocarcinoma negative 75 66 One adenocarcinoma nine benign Suspicious 3 One hyperplasia One hyperplasia one polyp Malignant 1 1 Adenocarcinoma Total 88 77 16 RESULTS: Eighty-eight cases were examined with an age range of 42-82. Review of the false negative case showed no malignant cells and is likely to represent a sampling problem. CONCLUSIONS: 1. The technique is useful in identifying low risk patients, only 16 of 88 had further histological investigation. 2. Increased experience and better recognition of the different cytological appearances should improve the diagnostic accuracy.
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