Proffered papers 10.30-11.15 monday 15 september 2003.

摘要

AIMS: (1) To identify the outcome status of women with borderline and mild dyskaryosis smears. (2)To determine whether the presence or absence of koilocytosis influences the outcome status. (3)To identify the proportion of women with borderline smears showing koilocytosis. MATERIALS AND METHODS: Borderline and mild dyskaryosis cervical smears diagnosed during January to March 1997 were identified from the laboratory database. Each slide was reviewed by two researchers independently, who then agreed a final consensus diagnosis. All slides were classified according to the presence or absence of koilocytosis. Slides were excluded from the study if the review diagnosis was negative, inadequate or high-grade dyskaryosis. The outcome status was classified according to the worst lesion identified histologically and/or cytologically during the 5-year follow-up period. RESULTS: 1974 women were identified with borderline or mild dyskaryosis cervical smears of which 1597 were included in the study. Table 1 shows the outcome status of these women. Table 2 shows the outcome of women with borderline and mild dyskaryosis smears with or without koilocytosis. Table 3 shows the proportion of borderline and mild dyskaryosis cervical smears with or without koilocytosis. CONCLUSIONS: (1)Sixty-eight per cent of women with a borderline cervical smear had a normal outcome. (2)Thirteen per cent of women with a borderline cervical smear developed a high-grade lesion. (3)The presence or absence of koilocytosis in borderline and mild dyskaryosis cervical smears does not appear to affect the outcome status of these women. (4)Twenty-four per cent of smears showing borderline nuclear changes were found to have koilocytosis.