Inflammatory cell types in nasal polyps

摘要

Dear Editor, Nasal polyposis is a common health problem affecting 4% of the world population.However, the exact pathogenesis is still unknown. Currently, there are no studies in the literature reporting the cellular types characterizing the surface of nasal polyps, just as there is no description of the correlations between different inflammatory cell types and their clinical features. The aim of this study was to investigate the different cell types, their frequency and the correlated symptoms [asthma, aspirin sensitivity (AS), aspirin sensitivity with asthma (AS-asthma)], family of atopy, asthma, AS, or nasal polyposis and recurrence rate in a group of 144 patients (66 female, 78 male; mean age 46 years) suffering from nasal polyps not associated with allergic rhinitis. Atopy was excluded by negative skin prick tests. The diagnosis of nasal polyposis was made using a fibre optic endo-scope (Vision Sciences ENT 2000 having a diameter of 3.4 mm; Orangeburg, NY, USA).