Antibacterial properties of synthesized Ag and Ag@SiO2 core-shell nanoparticles: a comparative study

摘要

Spherical bare silver nanoparticles (AgNPs) and silica-coated silver nanoparticles (Ag@SiO2) have been prepared using the one-step chemical reduction method. The optical, structural, and morphological studies were done by UV-visible absorption spectroscopy, X-ray diffraction (XRD), and transmission electron microscopy (TEM). The antibacterial effects of AgNP and Ag@SiO2 were further compared based on diameter of zone of inhibition and minimum inhibitory concentration (MIC) test against B. subtilis AST5-2, S. aureus ATCC 25923, S. marcescens AL2-16, and IC pneumoniae AWD5. Enhanced antibacterial activities were observed for Ag@SiO(2 )core-shell nanoparticles as compared to AgNPs against all tested bacteria. The results were attributed to the prolonged release of Ag (I) through porous silica shell that inhibits the growth of tested bacteria and also infers the possibility to be used in potential antibacterial applications.