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首页> 外文期刊>Cytometry, Part A: the journal of the International Society for Analytical Cytology >Circulating endothelial cells (CECs) and endothelial progenitor cells (CEPS) in peripheral blood (PB) flow cytometric detection in healthy subjects
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Circulating endothelial cells (CECs) and endothelial progenitor cells (CEPS) in peripheral blood (PB) flow cytometric detection in healthy subjects

机译:健康受试者外周血(PB)流式细胞仪检测循环内皮细胞(CEC)和内皮祖细胞(CEPS)

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摘要

Background: CECs play an important role in neovascularisation and tumor growth. CECs, resting (rCECs) and activated (aCECs), with CEPs are currently evaluated as potential biomarkers of anti-angiogenic therapy. This is important to correlate the level of CECs with disease status, known prognostic factors and response to treatment. As preliminary phase of a clinical study, we wanted to quantify, CECs and CEPs values of HS that will be utilized as controls vs cancer pts treated with antiangiogenetic drug. Methods: Samples of PB from 50 HC (M/F:25/25, median age 40 yrs) were analysed.
机译:背景:CEC在新血管形成和肿瘤生长中起重要作用。目前评估具有CEP的静息CEC(rCEC)和活化CEC(aCEC)作为抗血管生成疗法的潜在生物标志物。这对于将CEC的水平与疾病状况,已知的预后因素和对治疗的反应相关联非常重要。作为临床研究的初步阶段,我们想量化HS的CECs和CEPs值,这些值将用作对照与抗血管生成药物治疗的癌症患者的对照。方法:分析50 HC(M / F:25/25,中位年龄40岁)中的PB样品。

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