Ageing and physiological changes in rod-mediated dark adaptation

摘要

Clark et at have mentioned 'cross-sectional design' and 'fixation instability in participants with seriously impaired acuity' as the limitations of the study in their article published in the latest issue of the British Journal of Ophthalmology.However, one important limitation is that they have not compared the results of 'spectral domain optical coherence tomography and dark adaptation correlation' with normal age-matched controls without age-related maculopathy (ARM) and in patients with advanced ARM. The comparison of the dark adaptation in age-matched normal subjects attains importance as psychophysical and physiological studies in humans have demonstrated that a number of rod-mediated visual functions are compromised with age.