Efficacy and safety in older patient subsets in studies of endocrine monotherapy versus combination therapy in patients with HR+/HER2-advanced breast cancer: a review

Freedman Rachel A.; Tolaney Sara M.

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Efficacy and safety in older patient subsets in studies of endocrine monotherapy versus combination therapy in patients with HR+/HER2-advanced breast cancer: a review

机译：高龄患者子集中的疗效和安全性在人力资源+ / HER2晚期乳腺癌患者内分泌单疗法与联合治疗中的研究中的疗效和安全性：综述

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Purpose Prospective information regarding the tolerability and efficacy of endocrine therapy (ET) alone and in combination with targeted agents in older patients in the metastatic setting is limited. This review summarizes available trial data in this population.

机译：目的是关于内分泌治疗（ET）单独和与老年患者中的靶标菌在转移设定中的靶标菌的耐受性和疗效的预期信息有限。此审查总结了本人的可用试用数据。

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《Breast cancer research and treatment.》 |2018年第3期|共8页
作者
Freedman Rachel A.; Tolaney Sara M.;
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作者单位

Dana Farber Canc Inst Dept Med Oncol Breast Oncol Program 450 Brookline Ave Boston MA 02215 USA;

Dana Farber Canc Inst Dept Med Oncol Breast Oncol Program 450 Brookline Ave Boston MA 02215 USA;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Elderly; Breast cancer; Geriatric; CDK4/6 inhibitor; Ribociclib; Palbociclib;

机译：老年人;乳腺癌;老年人;CDK4 / 6抑制剂;Ribociclib;Palbociclib;
入库时间 2022-08-19 23:05:58

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1. Efficacy and safety in older patient subsets in studies of endocrine monotherapy versus combination therapy in patients with HR+/HER2-advanced breast cancer: a review [J] . Freedman Rachel A., Tolaney Sara M. Breast cancer research and treatment. . 2018,第3期

机译：高龄患者子集中的疗效和安全性在人力资源+ / HER2晚期乳腺癌患者内分泌单疗法与联合治疗中的研究中的疗效和安全性：综述
2. Is There Still a Role for Endocrine Therapy Alone in HR+/HER2-Advanced Breast Cancer Patients? Results from the Analysis of Two Data Sets of Patients Treated with High-Dose Fulvestrant as First-Line Therapy in the Real-World Setting: The EVA and GIM-13 AMBRA Studies [J] . Cazzaniga Marina Elena, Verusio Claudio, Ciccarese Mariangela, Breast care . 2020,第1期

机译：仍然存在单独的内分泌治疗在人力资源+ /海拔乳腺癌患者中的作用吗？在实际环境中分析高剂量氟斯特提治疗患者两种数据集的结果：EVA和GIM-13 AMBRA研究
3. Real-world effectiveness of everolimus-based therapy versus endocrine monotherapy and chemotherapy in patients of HR+/HER2-breast cancer with liver metastasis in the USA [J] . Lin Peggy L., Hao Yanni, Xie Jipan, Expert opinion on pharmacotherapy . 2015,第14期

机译：在美国，以依维莫司为基础的治疗与内分泌单一疗法和化学疗法对HR + / HER2乳腺癌并发肝转移的患者的实际疗效
4. Radium-223 Dichloride Monotherapy and Combination Therapy with Zoledronic Acid or Doxorubicin Improve Survival in a Mouse Model of Breast Cancer Bone Metastasis [C] . Jukka Rissanen, Mari Suominen, Rami K?k?nen, Molecular Medicine TRI-CON. . 2014

机译：镭-223二氯化物单疗法和组合治疗唑醇或多柔比星改善了乳腺癌骨转移的小鼠模型中的存活
5. A Retrospective Chart Review on Declination of Endocrine Therapy in Patients with Non-invasive Breast Cancer and Atypical Hyperplasia [D] . Ray, Brittany. 2020

机译：非侵入性乳腺癌和非典型增生患者内分泌治疗衰退的回顾图综述
6. Efficacy and Safety of Metronidazole Monotherapy versus Vancomycin Monotherapy or Combination Therapy in Patients with Clostridium difficile Infection: A Systematic Review and Meta-Analysis [O] . Rui Li, Laichun Lu, Yu Lin, -1

机译：甲硝唑单药疗法与万古霉素单药疗法或联合疗法在艰难梭菌感染患者中的疗效和安全性：系统评价和荟萃分析
7. Efficacy and Safety of Metronidazole Monotherapy versus Vancomycin Monotherapy or Combination Therapy in Patients with Clostridium difficile Infection: A Systematic Review and Meta-Analysis. [O] . Rui Li, Laichun Lu, Yu Lin, 2015

机译：甲硝唑单药治疗与万古霉素单药治疗或联合治疗对艰难梭菌感染患者的疗效和安全性：系统评价和meta分析。

Efficacy and safety in older patient subsets in studies of endocrine monotherapy versus combination therapy in patients with HR+/HER2-advanced breast cancer: a review

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