Interaction of insulin-like growth factor-I and insulin resistance-related genetic variants with lifestyle factors on postmenopausal breast cancer risk

Jung Su Yon; Ho Gloria; Rohan Thomas; Strickler Howard; Bea Jennifer; Papp Jeanette; Sobel Eric; Zhang Zuo-Feng; Crandall Carolyn

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Interaction of insulin-like growth factor-I and insulin resistance-related genetic variants with lifestyle factors on postmenopausal breast cancer risk

机译：胰岛素样生长因子-1和胰岛素抵抗相关遗传变异与生活方式因子的相互作用对绝经后乳腺癌风险的生活方式因子

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摘要

Genetic variants and traits in metabolic signaling pathways may interact with obesity, physical activity, and exogenous estrogen (E), influencing postmenopausal breast cancer risk, but these inter-related pathways are incompletely understood.

机译：代谢信号传导途径中的遗传变异和特征可以与肥胖，身体活动和外源性雌激素（E）相互作用，影响绝经后乳腺癌风险，但这些相关的途径不完全理解。

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来源
《Breast cancer research and treatment.》 |2017年第2期|共21页
作者
Jung Su Yon; Ho Gloria; Rohan Thomas; Strickler Howard; Bea Jennifer; Papp Jeanette; Sobel Eric; Zhang Zuo-Feng; Crandall Carolyn;
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作者单位

Univ Calif Los Angeles Sch Nursing Translat Sci Sect Jonsson Comprehens Canc Ctr 700 Tiverton;

Hofstra Northwell Sch Med Feinstein Inst Med Res Dept Occupat Med Epidemiol &

Prevent Great Neck;

Albert Einstein Coll Med Dept Epidemiol &

Populat Hlth Bronx NY 10467 USA;

Albert Einstein Coll Med Dept Epidemiol &

Populat Hlth Bronx NY 10467 USA;

Univ Arizona Ctr Canc Med &

Nutr Sci Tucson AZ USA;

Univ Calif Los Angeles David Geffen Sch Med Dept Human Genet Los Angeles CA 90095 USA;

Univ Calif Los Angeles David Geffen Sch Med Dept Human Genet Los Angeles CA 90095 USA;

Univ Calif Los Angeles Fielding Sch Publ Hlth Dept Epidemiol Los Angeles CA USA;

Univ Calif Los Angeles David Geffen Sch Med Div Gen Internal Med Dept Internal Med Los Angeles;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Insulin-like growth factor-I/insulin resistance-related genetic variant; Obesity; Physical activity; Exogenous estrogen; Breast cancer; Postmenopausal women;

机译：胰岛素样生长因子-i /胰岛素抵抗相关的遗传变异;肥胖;体育活动;外源性雌激素;乳腺癌;绝经后妇女;

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专利

1. Interaction of insulin-like growth factor-I and insulin resistance-related genetic variants with lifestyle factors on postmenopausal breast cancer risk [J] . Jung Su Yon, Ho Gloria, Rohan Thomas, Breast cancer research and treatment. . 2017,第2期

机译：胰岛素样生长因子-1和胰岛素抵抗相关遗传变异与生活方式因子的相互作用对绝经后乳腺癌风险的生活方式因子
2. Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer a [J] . Canzian F, McKay JD, Cleveland RJ, Cancer epidemiology, biomarkers and prevention: A publication of the American Association for Cancer Research . 2005,第10期

机译：与循环中的胰岛素样生长因子-I，胰岛素样生长因子结合蛋白-3和乳腺癌风险相关的生长激素合成途径的遗传变异：欧洲对癌症的前瞻性研究结果
3. Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease [J] . Sally L Ricketts, Katrijn L Rensing, Jeff M Holly, International Journal of Molecular Epidemiology and Genetics . 2011,第3期

机译：胰岛素样生长因子-I，胰岛素样生长因子结合蛋白3，IGF1和IGFBP3基因的遗传变异与冠心病风险的前瞻性研究
4. Genetic Association Study of Insulin-like Growth Factor-I (IGF-I) Gene with Curve Severity and Osteopenia in Adolescent Idiopathic Scoliosis [C] . YEUNG HY, TANG NL, LEE KM, International Research Society of Spinal Deformities . 2008

机译：胰岛素样生长因子-1（IGF-I）基因曲线严重程度和骨抑制性骨抑制症的遗传结合研究
5. Signaling interactions between prolactin and insulin-like growth factor-I: Implications for breast cancer progression and treatment. [D] . Carver, Kristopher Corey. 2009

机译：催乳素和胰岛素样生长因子-I之间的信号相互作用：对乳腺癌进展和治疗的影响。
6. Genetic variants and traits related to insulin-like growth factor-I and insulin resistance and their interaction with lifestyles on postmenopausal colorectal cancer risk [O] . Su Yon Jung, Thomas Rohan, Howard Strickler, -1

机译：与胰岛素样生长因子-I和胰岛素抵抗相关的遗传变异和性状及其与生活方式的关系对绝经后结直肠癌的风险
7. Genetic variants and traits related to insulin-like growth factor-I and insulin resistance and their interaction with lifestyles on postmenopausal colorectal cancer risk [O] . Jung Su Yon, Rohan Thomas, Strickler Howard, 2017

机译：与胰岛素样生长因子-I和胰岛素抵抗相关的遗传变异和性状及其与生活方式的关系，对绝经后结直肠癌的风险

Interaction of insulin-like growth factor-I and insulin resistance-related genetic variants with lifestyle factors on postmenopausal breast cancer risk

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