Cell Line Development Strategies for Difficult-to-Express Proteins

摘要

Before Hager began his presentation, he reminded the audience that this year is the 50th anniversary of the Apollo 11 Moon landing. In 1961, President Kennedy challenged the United States to put astronauts on the Moon by the end of that decade. When we embark on developing a new biologic entity, Hager said, it's no less arduous a journey, and it takes about the same time as it took to get to the Moon. For example, Keytruda (pembrolizumab) was first humanized in 2006 and ultimately approved in September 2014.