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首页> 外文期刊>Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie >MiR-345-5p functions as a tumor suppressor in pancreatic cancer by directly targeting CCL8
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MiR-345-5p functions as a tumor suppressor in pancreatic cancer by directly targeting CCL8

机译：MiR-345-5P通过直接靶向CCL8作为胰腺癌中的肿瘤抑制剂

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摘要

Background: Increasing evidence has demonstrated that microRNAs (miRNAs) are key regulators of human diseases and can serve as prognostic markers for several cancers, such as pancreatic ductal adenocarcinoma (PDAC). Previous studies have revealed various functions for miR-345-5p in several cancers. However, the role and potential mechanism of miR-345-5p in PDAC have not been resolved.
机译：背景：越来越多的证据表明MicroRNA（miRNA）是人类疾病的关键调节因子，并且可以作为几种癌症的预后标志物，例如胰腺导管腺癌（PDAC）。 以前的研究揭示了几种癌症中miR-345-5p的各种功能。 但是，尚未解决PDAC中MIR-345-5P的作用和潜在机制。

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  • 作者

    Mou Tinggang; Xie Fei; Zhong Pingyong; Hua Hao; Lai Liang; Yang Qin; Wang Jie;

  • 作者单位

    First Peoples Hosp Neijiang Dept Hepat Biliary Pancreat Surg Neijiang Sichuan Peoples R China;

    First Peoples Hosp Neijiang Dept Hepat Biliary Pancreat Surg Neijiang Sichuan Peoples R China;

    First Peoples Hosp Neijiang Dept Hepat Biliary Pancreat Surg Neijiang Sichuan Peoples R China;

    First Peoples Hosp Neijiang Dept Hepat Biliary Pancreat Surg Neijiang Sichuan Peoples R China;

    First Peoples Hosp Neijiang Dept Hepat Biliary Pancreat Surg Neijiang Sichuan Peoples R China;

    First Peoples Hosp Neijiang Dept Gastroenterol Neijiang Sichuan Peoples R China;

    First Peoples Hosp Neijiang Dept Hepat Biliary Pancreat Surg Neijiang Sichuan Peoples R China;

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  • 正文语种 eng
  • 中图分类 治疗学;
  • 关键词

    PDAC; miR-345-5p; CCL8; Proliferation; Migration; Invasion;

    机译：pdac;mir-345-5p;ccl8;增殖;迁移;入侵;

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