MMP-9 secreted by tumor associated macrophages promoted gastric cancer metastasis through a PI3K/AKT/Snail pathway

Liu Lin; Ye Yu; Zhu Xiumei

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MMP-9 secreted by tumor associated macrophages promoted gastric cancer metastasis through a PI3K/AKT/Snail pathway

机译：通过肿瘤相关巨噬细胞分泌的MMP-9通过PI3K / AKT /蜗牛途径促进胃癌转移

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Purpose: The distant metastasis in gastric has become an obstacle for treatment in clinic. However, the underlying mechanism is not well illustrated. Here, our aim is to reveal the mechanism and try to explore the potential strategy to overcome the distant metastasis.

机译：目的：胃中的远距离转移已成为临床治疗的障碍。但是，潜在机制没有很好地说明。在这里，我们的目标是揭示机制并试图探索克服遥远的转移的潜在战略。

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《Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie》 |2019年第117期|共8页
作者
Liu Lin; Ye Yu; Zhu Xiumei;
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作者单位

Henan Prov Peoples Hosp Dept Pain 7th Weiwu Rd Zhengshou Henan Peoples R China;

Hangzhou Red Cross Hosp Gen Surg Dept 208 Huancheng East Rd Hangzhou Zhejiang Peoples R China;

First Peoples Hosp Guannan Dept Anaesthesia 2th North Taizhou Rd Lianyungang Jiangsu Peoples R;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Gastric cancer; MMP-9; PI3K/AKT; Epithelial to mesenchymal transition;

机译：胃癌;MMP-9;PI3K / AKT;上皮进行间充质转换;

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专利

1. MMP-9 secreted by tumor associated macrophages promoted gastric cancer metastasis through a PI3K/AKT/Snail pathway [J] . Liu Lin, Ye Yu, Zhu Xiumei Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2019,第117期

机译：通过肿瘤相关巨噬细胞分泌的MMP-9通过PI3K / AKT /蜗牛途径促进胃癌转移
2. Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer. [J] . Yoo YA, Kang MH, Lee HJ, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2011,第22期

机译：声波刺猬通路通过激活Akt，EMT和MMP-9途径促进胃癌的转移和淋巴管生成。
3. NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-κB/Snail axis and predicts outcome of the patients [J] . Jun-yan Liu, Lei Jiang, Tao He, Cell death & disease. . 2019,第3期

机译：NETO2通过激活PI3K / Akt /NF-κB/ Snail轴促进胃癌细胞的侵袭和转移，并预测患者的预后
4. Ang-2 promoting proliferation of SW1116 colon cancer cells through PI3K/Akt pathways [C] . Hong Zhang Ji, Yang Wen Chun, Ping Wang Ai, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：Ang-2通过PI3K / Akt途径促进SW1116结肠癌细胞的增殖
5. DLX4 homeoprotein promotes PI3K/Akt anti-apoptosis pathway in ER negative breast cancer cells through upregulation of VEGFA. [D] . Wu, Weiwei. 2010

机译：DLX4同源蛋白通过上调VEGFA促进ER阴性乳腺癌细胞中的PI3K / Akt抗凋亡途径。
6. NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-κB/Snail axis and predicts outcome of the patients [O] . Jun-yan Liu, Lei Jiang, Tao He, 2019

机译：NETO2通过激活PI3K / Akt /NF-κB/ Snail轴促进胃癌细胞的侵袭和转移并预测患者的预后
7. Bladder cancer cell‑secreted exosomal miR‑21 activates the PI3K/AKT pathway in macrophages to promote cancer progression [O] . Fan Lin, Hu‑Bin Yin, Xin‑Yuan Li, 2019

机译：膀胱癌细胞分泌的外泌体miR-21在巨噬细胞中激活PI3K / AKT途径以促进癌症进展

MMP-9 secreted by tumor associated macrophages promoted gastric cancer metastasis through a PI3K/AKT/Snail pathway

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