Apocrine carcinoma of the breast diagnosed on fine needle aspiration cytology.

摘要

Apocrine cells are encountered frequently in fine needle aspiration (FNA) smears from benign breast lesions. While apocrine atypia is an uncommon finding in histologic material from breast lesions, in cytologic preparations, atypical apocrine cells are frequent,1 occurring in flbrocystic condition, duct papil-loma, fibroadenoma, adenomyoepithelioma and apocrine carcinoma (AC), an uncommon variant of breast carcinoma. Cytologic features of apocrine carcinoma have been reported in relatively few cases. Malignant cells in AC have abundant, eosinophilic cytoplasm, well-defined cell margins; large, vesicular nuclei; and macronucleoli.