Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior

Mackey Scott; Chaarani Bader; Kan Kees-Jan; Spechler Philip A.; Orr Catherine; Banaschewski Tobias; Barker Gareth; Bokde Arun L. W.; Bromberg Uli; Buechel Christian; Cattrell Anna; Conrod Patricia J.; Desrivieres Sylvane; Flor Herta; Frouin Vincent; Gallinat Juegen; Gowland Penny; Heinz Andreas; Ittermann Bernd; Martinot Marie-Laure Paillere; Artiges Eric; Nees Frauke; Papadopoulos-Orfanos Dimitri; Poustka Luise; Smolka Michael N.; Jurk Sarah; Walter Henrik; Whelan Robert; Schumann Gunter; Althoff Robert R.; Garavan Hugh

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Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior

机译：与冲动有关的脑区介绍了早期逆境对反社会行为的影响

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摘要

BACKGROUND: Individual differences in impulsivity and early adversity are known to be strong predictors of adolescent antisocial behavior. However, the neurobiological bases of impulsivity and their relation to antisocial behavior and adversity are poorly understood.

机译：背景：已知冲动和早期逆境的个人差异是青少年反社会行为的强预测因子。然而，脉冲性的神经生物学基础及其与反社会行为和逆境的关系都很清楚。

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来源
《Biological psychiatry》 |2017年第4期|共8页
作者
Mackey Scott; Chaarani Bader; Kan Kees-Jan; Spechler Philip A.; Orr Catherine; Banaschewski Tobias; Barker Gareth; Bokde Arun L. W.; Bromberg Uli; Buechel Christian; Cattrell Anna; Conrod Patricia J.; Desrivieres Sylvane; Flor Herta; Frouin Vincent; Gallinat Juegen; Gowland Penny; Heinz Andreas; Ittermann Bernd; Martinot Marie-Laure Paillere; Artiges Eric; Nees Frauke; Papadopoulos-Orfanos Dimitri; Poustka Luise; Smolka Michael N.; Jurk Sarah; Walter Henrik; Whelan Robert; Schumann Gunter; Althoff Robert R.; Garavan Hugh;
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作者单位

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

Heidelberg Univ Dept Child &

Adolescent Psychiat &

Psychotherapy Cent Inst Mental Hlth Med Fac;

Kings Coll London Ctr Neuroimaging Sci Inst Psychiat Psychol &

Neurosci London England;

Trinity Coll Dublin Discipline Psychiat Sch Med Dublin Ireland;

Univ Med Ctr Hamburg Eppendorf Hamburg Germany;

Kings Coll London MRC Social Genet &

Dev Psychiat Ctr Inst Psychiat Psychol &

Neurosci London;

Univ Montreal Dept Psychiat CHU Ste Justine Hosp Montreal PQ Canada;

Univ Montreal Dept Psychiat CHU Ste Justine Hosp Montreal PQ Canada;

Kings Coll London MRC Social Genet &

Dev Psychiat Ctr Inst Psychiat Psychol &

Neurosci London;

Heidelberg Univ Dept Cognit &

Clin Neurosci Cent Inst Mental Hlth Med Fac Mannheim Mannheim;

CEA Saclay Ctr Neurospin CEA Paris France;

Univ Med Ctr Hamburg Eppendorf Dept Psychiat &

Psychotherapy Hamburg Germany;

Univ Nottingham Sir Peter Mansfield Imaging Ctr Sch Phys &

Astron Univ Pk Nottingham England;

Charite Dept Psychiat &

Psychotherapy Campus Charite Mitte Berlin Germany;

Phys Tech Bundesanstalt Berlin Germany;

Univ Paris 05 Dept Adolescent Psychopathol &

Med Sorbonne Paris Cite Univ Paris Sud Cochin Hosp;

Heidelberg Univ Dept Cognit &

Clin Neurosci Cent Inst Mental Hlth Med Fac Mannheim Mannheim;

CEA Saclay Ctr Neurospin CEA Paris France;

Heidelberg Univ Dept Child &

Adolescent Psychiat &

Psychotherapy Cent Inst Mental Hlth Med Fac;

Tech Univ Dresden Dept Psychiat Dresden Germany;

Tech Univ Dresden Dept Psychiat Dresden Germany;

Charite Dept Psychiat &

Psychotherapy Campus Charite Mitte Berlin Germany;

Univ Coll Dublin Dept Psychol Dublin Ireland;

Kings Coll London MRC Social Genet &

Dev Psychiat Ctr Inst Psychiat Psychol &

Neurosci London;

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

Univ Vermont Dept Psychiat Burlington VT 05401 USA;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Adversity; Antisocial behavior; Development; Impulsivity; Temporal discounting; Voxel-based morphometry;

机译：逆境;反社会行为;发展;冲动;时间折扣;基于体素的形态学;

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专利

1. Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior [J] . Mackey Scott, Chaarani Bader, Kan Kees-Jan, Biological psychiatry . 2017,第4期

机译：与冲动有关的脑区介绍了早期逆境对反社会行为的影响
2. RELATION BETWEEN CHILDHOOD ADVERSITY, EXTERNALIZING BEHAVIOR, AND SUBSTANCE USE IN ADOLESCENCE: MEDIATING EFFECTS OF BRAIN PROCESSES [J] . Trucco E. M., Fava N. M., Martz M. E., Alcoholism: Clinical and experimental research . 2017,第Suppla1期

机译：儿童逆境，外化行为与青春期内物质的关系：脑过程中的介导影响
3. Impact of Family and Friends on Antisocial Adolescent Behavior: The Mediating Role of Impulsivity and Empathy [J] . lvarez-Garca David, Gonzlez-Castro Paloma, Nez Jos Carlos, Frontiers in Psychology . 2019,第2期

机译：家庭与朋友对反社会青少年行为的影响：冲动和移情的中介作用
4. TiO_2-nanowired delivery of cerebrolysin thwarts exacerbation of sleep deprivation induced decline in regional brain derived neurotrophic factor, brain pathology and behavioral dysfunctions following emotional stress [C] . Aruna Sharma, Dafin Fior Muresanu, Jose Vicente Lafuente, Annual TechConnect World Innovation Conference Expo;Annual Nanotech Conference Expo;National SBIR/STTR Conference . 2017

机译：TiO_2纳米线递送的脑溶素可阻止睡眠剥夺的加剧，从而导致情绪应激导致局部脑源性神经营养因子，脑病理和行为功能障碍的下降
5. Effects of heroin on sickness behavior and proinflammatory mediators in associated brain regions. [D] . Wagner, Alison Fay. 2010

机译：海洛因对相关脑区疾病行为和促炎介质的影响。
6. Social Adversity and Antisocial Behavior: Mediating Effects of Autonomic Nervous System Activity [O] . Shawn E. Fagan, Wei Zhang, Yu Gao -1

机译：社交逆境与反社交行为：自主神经系统活动的中介作用
7. Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior [O] . Mackey, Scott, Chaarani, Bader, Kan, Kees-Jan, 2016

机译：与冲动有关的大脑区域介导逆境对反社会行为的影响

Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior

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