THE POTENTIAL ROLE OF FIRST TRIMESTER MATERNAL SERUM PP13 AND SECOND-TRIMESTER UTERINE ARTERY DOPPLER PULSATILITY INDEX AS MARKERS OF PRE-ECLAMPSIA AMONG HIGH RISK EGYPTIAN PREGNANT FEMALES

摘要

Preeclampsia is a widespread vasospasm and vascular endothelial dysfunction that usually occurs after 20 weeks gestation. Uterine artery Doppler is a good sensitive predictor. PP13 (as a chemical predictor) was claimed to provide similar results.Objective. To evaluate whether first trimester maternal serum placenta protein 13 (PP13) and the second trimester uterine artery Doppler pulsatility index can predict pre-eclampsia among high risk Egyptian pregnant females.Design. The study took place in obstetric clinic of Kasr Elaini Hospital (Faculty of Medicine - Cairo University) in the period October 2011 - August 2012.