Biodegradable multi-liposomal containers

摘要

Here we describe biodegradable multi-liposomal core-shell containers. They are made of a poly-L-lactide-polyethyleneoxyde-poly-L-lactide triblock-copolymer core covered by electrostatically adsorbed liposomes. The liposomes retain their integrity after adsorption, which allows them to be used for encapsulating bioactive compounds. The multi-liposomal containers eventually decompose, by being attacked by hydrolytic enzymes, which makes them promising for use in drug delivery.