Colorimetric detection of Hg2+ based on inhibiting the peroxidase-like activity of DNA-Ag/Pt nanoclusters

摘要

This paper reported that the peroxidase-like activity of DNA-Ag/Pt nanoclusters (NCs) can be inhibited selectively by Hg2+. The interaction between Hg2+ and the DNA-Ag/Pt NCs was discussed through characterization by TEM, DLS and XPS, etc. It was found that the integration of both Hg-0 and Hg2+ to the DNA-Ag/Pt NCs resulted in the DNA-Ag/Pt NCs aggregation and the decrease of Pt2+ content on the DNA-Ag/Pt NCs surface, which finally impaired their catalytic activity. Based on the above mechanism, a colorimetric detection for Hg2+ was developed with a detection limit (LOD) of 5.0 nM and a linear range from 10 nM to 200 nM. The method was highly selective toward Hg2+ over other common metal ions, low-cost and simple, which facilitated the application of detecting Hg2+ in tap water.