Neutralizing Antibodies Against Adeno-associated virus (AAV)2 Capsids in LHON Gene Therapy Clinical Trial Patients: An Update

Koilkonda Rajeshwari D.; Feuer William J.; Schiffman Joyce; Davis Janet L.; Porciatti Vittorio; Gonzalez Phillip; Lam Byron L.; Guy John

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Neutralizing Antibodies Against Adeno-associated virus (AAV)2 Capsids in LHON Gene Therapy Clinical Trial Patients: An Update

机译：中和抗腺相关病毒（AAV）的抗体在LHON基因治疗临床试验患者中2粒衣物：更新

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来源
《Investigative ophthalmology & visual science》 |2017年第8期|共3页
作者
Koilkonda Rajeshwari D.; Feuer William J.; Schiffman Joyce; Davis Janet L.; Porciatti Vittorio; Gonzalez Phillip; Lam Byron L.; Guy John;
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作者单位

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

Bascom Palmer Eye Inst Ophthalmol Miami FL 33136 USA;

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原文格式 PDF
正文语种 eng
中图分类眼科学;
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专利

1. Neutralizing Antibodies Against Adeno-associated virus (AAV)2 Capsids in LHON Gene Therapy Clinical Trial Patients: An Update [J] . Koilkonda Rajeshwari D., Feuer William J., Schiffman Joyce, Investigative ophthalmology & visual science . 2017,第8期

机译：中和抗腺相关病毒（AAV）的抗体在LHON基因治疗临床试验患者中2粒衣物：更新
2. Neutralizing Antibodies Against Adeno-associated virus (AAV)2 Capsids in LHON Gene Therapy Clinical Trial Patients: An Update [J] . Koilkonda Rajeshwari D., Feuer William J., Schiffman Joyce, Investigative ophthalmology & visual science . 2017,第8期

机译：中和抗腺相关病毒（AAV）的抗体在LHON基因治疗临床试验患者中2粒衣物：更新
3. Assessment of Neutralizing Antibodies Against Adeno-associated virus (AAV)2 Capsids in Serum and Ocular Fluid Samples of Leber' Hereditary Optic Neuropathy (LHON) Gene Therapy Clinical Trial Patients [J] . Koilkonda Rajeshwari D., Feuer William J., Schiffman Joyce C., Investigative ophthalmology & visual science . 2016,第12期

机译：评估血清血清血清和眼部液体样品中的腺相关病毒（AAV）2衣物的中和抗体（LHON）基因治疗临床试验患者
4. Transmission Electron Tomography of Adeno-Associated Virus (AAV) [C] . G. Gao, G. M. Hendricks Microscopy and microanalysis.;Microscopy and microanalysis. . -1

机译：腺相关病毒（AAV）的透射电子断层扫描
5. Studies of canine parvovirus capsid: Assembly, disassembly and antibody neutralization. [D] . Yuan, Wen. 2000

机译：犬细小病毒衣壳的研究：组装，拆卸和抗体中和。
6. Monoclonal Antibodies against the Adeno-Associated Virus Type 2 (AAV-2) Capsid: Epitope Mapping and Identification of Capsid Domains Involved in AAV-2–Cell Interaction and Neutralization of AAV-2 Infection [O] . Christiane E. Wobus, Barbara Hügle-Dörr, Anne Girod, 2000

机译：腺相关病毒2型（AAV-2）衣壳的单克隆抗体：抗原表位定位和涉及AAV-2的衣壳域的鉴定-细胞相互作用和AAV-2感染的中和。
7. Prevalence of Neutralizing Antibodies Against Adeno-Associated Virus (AAV) Types 2, 5, and 6 in Cystic Fibrosis and Normal Populations: Implications for Gene Therapy Using AAV Vectors [O] . Christine L. Halbert, A. Dusty Miller, Sharon Mcnamara, 2006

机译：患有腺相关病毒（AAV）类型2,5和6型中和抗体的患病率在囊性纤维化和正常群体中：使用AAV载体对基因治疗的影响
8. Guidance for Industry. Supplemental Guidance on Testing for Replication Compentent Retrovirus in Retroviral Vector Based Gene Therapy Products and During Follow-up of Patients in Clinical Trials Using Retroviral Vectors. [R] . 2000

机译：工业指南。基于逆转录病毒载体的基因治疗产品和临床试验患者随访期间使用逆转录病毒载体检测复制耐受性逆转录病毒的补充指南。

Neutralizing Antibodies Against Adeno-associated virus (AAV)2 Capsids in LHON Gene Therapy Clinical Trial Patients: An Update

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